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心脑血管疾病患者载脂蛋白(a)多态性研究 被引量:4

Apolipoprotein (a) phenotgpes of patients with mgo-cardial infarction
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摘要 对125例心脑血管疾病患者(心肌梗塞69例,脑卒中56例)进行了血清载脂蛋白(a)[apo(a)]表型和脂蛋白(a)[Lp(a)]浓度检测。并与190名健康人对照分析。结果表明,apo(a)表型在心脑血管疾病患者与对照组之间的分布存在明显差异(P<0.025),apo(a)表型的分子量与其血清Lp(a)浓度有显著相关性(心脑血管疾病组,r=一0.93,对照组r=一0.92,P<0.005)。 e studied apolipoprotein (a ) (apo (a) ) pheno-types of 69 myocardial infarction survivors and 56stroke patients, and compared them with those of 190healthy Chinese. The distribution of apo(a) phenotypefrequency in cardio-cerebrovascular disease patientswas different from those uf cnntrols.The frequency ofthe phenotypes B, S1 and S2 in patients was remark-ably higher than that in controls within the same sin-gle-band apo (a) phenotype. Moreover. the Lp(a)serum concentrations in CCVD patients were signifi-cantly higher than those in controls within the samesingle-band apo (a ) phenotype.
出处 《中华医学杂志》 CAS CSCD 北大核心 1995年第3期149-151,共3页 National Medical Journal of China
关键词 脂蛋白类 心肌梗塞 脑血管意外 诊断 Lipoprotein (a) PhenotypeMyocardial infarction Cerebrovascular disorders(Origuial arlirte on page 149)
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参考文献2

  • 1李建军,中华医学检验杂志,1994年,1卷,22页
  • 2庄一义,中华医学杂志,1992年,72卷,162页

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