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盐酸左西替利嗪联合雷尼替丁治疗慢性荨麻疹疗效观察 被引量:3

The effect of combineing levocetirizine hydrochloride and ranitidinein in the treatment of chronic urticaria
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摘要 目的探讨慢性荨麻疹的有效治疗方法。方法选择慢性荨麻疹患者70例,随机分为治疗组和对照组各35例。治疗组服盐酸左西替利嗪5mg/d,雷尼替丁300mg/d,对照组服盐酸左西替利嗪5mg/d,两组连服21d。结果治疗组有效率91.4%,对照组有1例退出外,完成治疗34例,有效率76.5%。两组比较,差异有显著意义(χ2=7.223,P<0.01)。结论盐酸左西替利嗪联合雷尼替丁治疗慢性荨麻疹较单用盐酸左西替利嗪效果好。 Objective To investigate the therapeutic efficiency of the combined levocetirizine hydrochloride and ranitidine in the treatment of chronic urticaria,providing more therapeutic methods for chronic urticaria.Methods 70 cases of chronic urticaria were chosen.The patients were randomly divided into therapeutic and control group,each group had 35 patients respectively.The patients of the therapeutic group were treated with levocetirizine hydrochloride 5mg/day and ranitidine 300mg/day and the patients of the control group were only treated with levocetirizine hydrochloride 5mg/day.Two groups were treated continuously for 21 days.Results The effective rate of 91.4% was obtained in the therapeutic group.One of the patients in the control group withdrawed.The effective rate of 76.5% was obtained in 34 patients who received treatment.The difference between 2 groups is significant(χ2=7.223,P<0.01).Conclusion Combined levocetirizine hydrochloride and ranitidine is better than only use of levocetirizine hydrochloride in the treatment of chronic urticaria.
出处 《中国基层医药》 CAS 2005年第6期692-693,共2页 Chinese Journal of Primary Medicine and Pharmacy
关键词 盐酸左西替利嗪 雷尼替丁 治疗 慢性荨麻疹 疗效观察 Urticaria Histamine H1 antagonists
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  • 1Gillard M,Van der Perren C,Massingham R,et al.Binding characteristics of [3H]levocetirizine to cloned human H1-histamine-receptors expressed in CHO cells.Inflamm Res,2002,51 Suppl 1:S77-S78.
  • 2Devalia JL,De Vos C,Hanotte F,et al.A randomized,doubleblind,crossover comparison among cetirizine,levocetirizine,and ucb 28557 on histamine-induced cutaneous responses in healthy adult volunteers.Allergy,2001,56:50-57.
  • 3Wang DY,Hanotte F,De Vos C,et al.Effect of cetirizine,levocetirizine,and dextrocetirizine on histamine-induced nasal response in healthy adult volunteers.Allergy,2001,56:339-343.
  • 4Clough GF,Boutsiouki P,Church MK.et al.Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal,flare,and itch in human skin.Allergy,2001,56:985-988.
  • 5Thomson L,Blaylock MG,Sexton DW,et al.Cetirizine and levocetirizine inhibit eotaxin-induced eosinophil transendothelial migration through human dermal or lung microvascular endothelial cells.Clin Exp Allergy,2002,32:1187-1192.
  • 6Leynadier F,Mees K,Arendt C,et al.Efficacy and safety of levocetirizine in seasonal allergic rhinitis.Acta Otorhinolaryngnl Belg,2001,55:305-312.
  • 7Baltes E,Coupez R,Giezek H,et al.Absorption and disposition of levocetirizine,the eutomer of cetirizine,administered alone or as cetirizine to healthy volunteers.Fundam Clin Pharmacol,2001,15:269-277.
  • 8Gandon JM,Allain H.Lack of effect of single and repeated doses of levocetirizine,a new antihistamine drug,on cognitive and psychomotor functions in healthy volunteers.Br J Clin Pharmacol,2002,54: 51-58.
  • 9张晓宁,中华整形烧伤外科杂志,1989年,5卷,213页
  • 10吕屏,上海免疫学杂志,1986年,6卷,231页

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