摘要
肺癌是我国最常见的恶性肿瘤之一。为提高肺癌的诊治率，我们对肺癌血清学的诊断方法不断进行研究、改进，以期建立一种操作简便，结果可信、肺癌检出率高的检查方法。本文采用组合单克隆抗体，经醋酸纤维薄膜电泳法，对７０例肺癌患者血清及１００例正常人血清进行了检测。结果显示，肺癌血清中癌相关抗原的检出率为８３％，正常人血清组的假阳性率为１０％，误诊率小于３０％，故此方法有诊断应用价值。
Lung cancer is one of the most common
cancers in our country. We constantlystudy to improve the diagnostic methods of lung cancer
in order to establish a simple, reliable andhigh detection method. In this paper 70 cases of
serum in patient with lung cancer and 100 casesof serum in normal individual were detected by
electrophoresis and enzyme staining using monocl-onal antibodies by “cock-tail”. The
results showed that the positive rate of tumor associated antigen(TAA) in the lung cancer cases
was 83% while positive rate of TAA in the normal individualwas l0%. The diagnostic mistake
rate(false negative rate plus false positive rate) was less than3o%. Therefore it is an useful
method to serological diagnosis in lung cancer.
出处
《军医进修学院学报》
CAS
1994年第2期79-81,共3页
Academic Journal of Pla Postgraduate Medical School
关键词
肺肿瘤
血清学诊断
单克隆抗体
醋酸纤维薄膜电泳
lung neoplasms
serodiagnosis
monoclonal antibodies
electrophoresis, cellulose ace-tate
