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国产加替沙星注射液治疗肺部细菌感染临床观察 被引量:2

Clinical observation of domestic gatifloxacin injection in the treatment of lung bacterial in fections
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摘要 目的评价国产加替沙星注射液治疗肺部感染的临床疗效、细菌清除率和安全性。方法选择肺部感染住院患者60例,分别使用加替沙星和左旋氧氟沙星治疗,不同时用其他抗生素。分别观察两组的有效率和细菌清除率。结果加替沙星组和左氧氟沙星组治疗有效率分别为73.3%和66.7%。细菌清除率分别为75.9%和75%,两组无明显差异。两组不良反应率均为6.67%。结论国产加替沙星注射液治疗肺部感染有效、安全。 Objective To compare the clinical efficacy,bacterial eradication rate and safety of domestic gatifloxacin in treating lung bacterial infections.Methods Sixty in -patients of lung bacterials infections were treated with gatifloxacin injection(30) and levofloxacin injection(30),with no addition of other antibiotics.We observed the efficacy rate and bacterial eradication rate of two group respectively.Results The efficacy rate and bacterial eradication were 73.3%,75.9% in the gatifloxacin,and 66.7%,75% in the levofloxacin.No significant difference in the above figures between the two groups.The clinical adverse reaction rates were both 6.67%.Conclusion Domestic gatifloxacin injection is effective and safe in treating lung bacterial infections.[
作者 方明 梅晓冬
出处 《安徽医学》 2005年第3期191-192,188,共3页 Anhui Medical Journal
关键词 国产药品 加替沙星注射液 药物治疗 肺部细菌感染 左氧氟沙星 Gatifloxacin Levofloxacin Lung bacterial infection
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  • 1Ping WU, Laura E L, Renneth L D, et,al, mechanism of action of the Des- F (6)quinolone BMS 284756 measured by supercoiling inhibition and cleavable complex assays. Antimicrob Agents Chemother,2001 , 45 (14) : 3660.
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同被引文献4

  • 1翁心华,卢洪洲.临床常见耐药菌及其抗菌治疗的研究进展[J].中国实用内科杂志,2004,24(8):449-451. 被引量:14
  • 2林萍,赵力波,贾霜.社区获得性肺炎的病因及治疗原则[J].中国药业,2006,15(6):63-64. 被引量:10
  • 3Sturenburg E,Mack D.EXtended spectrumbeta Lactamass;impucations for the clinical microbe ology laboratorg,therapy,and imfection control[J].J Infect Dis,2003,47(4):273-295.
  • 4Hoban DJ,Doem GV,Fluit AC,et al.Worldwide prevalence of antimicrobial resistance in Streptococcus pneumoniae,Haemophilus influenzae and Moraxellacatarrhailis in the SENTRY antimicrobial surveillance program,1997-1999[J].Clin Infect Dis,2001,32(suppl2):S81-S83.

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