摘要
目的: 探讨新生儿先天性心脏畸形的早期诊断及产前致病因素。方法: 采用以医院为基础的监测方法收集资料。调查对象为孕28周至产后7d在我院住院分娩的围产儿,包括活产、死胎和死产。所有病例均经彩色多普勒超声心动图(简称彩超)诊断,死亡病例经尸解证实。结果:共监测围产儿6518例,检出新生儿先天性心脏畸形43例,发生率为65. 97 /万,其中单发心脏畸形35例,占81. 40 /万,心脏外合并畸形8例,占18 60%。先天性心脏病发生率由2000年的56. 40 /万上升为2004年的80. 24 /万。城镇高于乡村,无明显性别差异。结论:先天性心脏畸形的发生率有上升趋势,彩超为确诊的主要手段。孕早期各种致畸因子与先天性心脏畸形的发生有一定关系。
Objective:To investigate the risk factors and diagnosis of neonatal congenital heart malformation. Methods:Hospital-based monitoring provided data that included perinatal cases ranging from 28 gestational weeks to 7 days after delivery, including live and still births. Colored Doppler echocardiography was conducted in all the cases, and autopsy for dead cases for confirmation. Results:From a total of 6518 monitored cases, 43 cases of congenital heart malformation were found, with a prevalence rate of 65.97 per 10,000. Thirty-five of these were of simple heart defect, with a prevalence rate of 81.40%, and 8 were of complicated heart defect, with a prevalence rate of 18.60%. The incidence rate has risen from 56.40 per 10,000 in 2000 to 80.24 per 10,000 in 2004, with a higher rate in urban areas vs rural areas, and no significant difference between both genders. Conclusions: There is a tendency of rise for the incidence of congenial heart malformation, with the colored Doppler echocardiography as the major diagnostic method. Various risk factors during early pregnancy are to a certain extent related to the incidence of congenial heart malformation.
出处
《广州医学院学报》
2005年第1期56-58,共3页
Academic Journal of Guangzhou Medical College
关键词
新生儿
先天性心脏畸形
newborn
congenital heart malformation
