摘要
该研究系统观察了92例慢性肺心病急性发作期患者使用4类6种血管扩张药物,其中包括硝普钠、氨力农、米力农、维拉帕米、地尔硫(艹卓)、卡托普科,以及吸入低浓度一氧化氮和施行机械通气两种方法的治疗效果。并各自比较使用前后其血流动力学及氧动力学变化。观察结果表明,上述药物及方法均可有效地降低肺动脉压力、阻力,有良好的急性血流动力学效应及氧动力学效应。
Responses have been observed and compared in 92 patients at acute episode of chronic pulmonary heart disease caused by chronic obstructive pulmonary disease (COPD). The patients were given one of 6 vasodilators including sodium nitroprusside, amrinone, milrinone, verapamil, diltiazem and captopril, the inhalation of NO and -mechanical ventilation respectively. The changes in patients' hemodynamics and oxygen - dynamics prior to and after each treatment have showed that the above - mentioned regimens reduced the pulmonary arterial pressure and resistance effectively, and had good acute hemodynamic and oxygen - dynamic effects. The characteristics and the indications of these, vasodilators were also evaluated, which might be valuable for the selection of vasodilator in clinical practice .
出处
《中国医药导刊》
1999年第2期18-21,共4页
Chinese Journal of Medicinal Guide
关键词
慢性肺心病
急性发作期
肺动脉高压
治疗
chronic obstructive pulmonary disease
pulmonary hypertension