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单纯性肥胖儿童下丘脑-垂体-肾上腺轴的功能状况 被引量:2

THE STATE OF HPAFUNCTION IN CHILDREN WITH SIMPLE OBESITY
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摘要 通过放射免疫法测定79例单纯性肥胖儿童血清皮质醇及地塞米松抑制试验,并与70例正常儿童比较。发现单纯性肥胖儿童血清皮质醇轻度增高,下丘脑—垂体—肾上腺轴关系平衡,提示单纯性肥胖儿存在肾上腺皮质功能改变。隔夜地塞米松抑制试验与传统的小剂量地塞米松抑制试验比较,其方法简便、结果可靠,尤其适合肥胖儿童门诊筛查。 y radioimmunoassay,serum cortisone level and dexamethasone suppression test in 79 childrenwith simple obesity were dertermined and compared with those in 70 normal children. The resultsshowed that serum cortisone level in ehildren with sunple obesity inereased slightly and therelation of HPAaxis was balanced. It suggests that there has been some change in adrcnal functionin children with sunple obesity. Compared with traditional low dosage dexamethasone suppressiontest,the dexamethasone suppression test of the previous night is simple,accurate and especiallysuitable for screening of obesity children at the outpatient department.
出处 《重庆医科大学学报》 CAS CSCD 1994年第1期46-48,共3页 Journal of Chongqing Medical University
关键词 儿童 肥胖病 皮质醇 下丘脑 垂体 Child Simple Obesity Cortisone
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