摘要
采用高营养素──优特力生对２１例肺心病呼吸衰竭人工通气患者进行４周管饲营养支持（能量３７～４５ｋｃａｌ·ｋｇ￣（－１）·ｄ￣（－１），蛋白质１４０～１．６７ｇ·ｋｇ￣（－１）·ｄ￣（－１），测定人体测量值及血清白蛋白、前白蛋白，并与１５例普通管饲的通气患者（其分别为２４～２９ｋｃａｌ·ｋｇ￣（－１）·ｄ￣（－１）和０．９２～１．０９ｇ·ｋｇ￣（－１）·ｄ￣（－１））作对比。通气１周末，两组病人均发生混合性营养不良；第２周末，实验组血清前白蛋白已接近正常，并显著高于对照组；第４周末，实验组血清白蛋白、前白蛋白均恢复正常，而对照组仍低于正常，人体测量值两组无差异。说明管饲优特力生能早日消除此类病人混合性营养不良状态，并达到正氮平衡。
wentyone mechanically ventilated patients with acute exacerbation of cor pulmonale had received home made“Nutritient”via nasal gastric tube as energy and protein support for four weeks(energysupplement 37-45 kcal·kg￣(-1)·d￣(-1), protein 1.40-1.67g·kg￣(-1)·d￣(-1)). Anthropometry,serum albumin,serum prealbumin were measured on the lst day and at the end of the 1st, 2nd,4th week of ventilation. The results were compared with those in 15 age-matehed ventilated patients who received routine hospital nasal gastric feeding(energy 24-29 kcal· kg￣(-1)·d￣(-1), protein:0.92-1.09g·kg￣(-1)·d￣(-1)).All patients were in protein derldent type malnutrition. At the end of the lst week of ventilation, serum albumin droped significantly in both groups,resulting in a status of mixed type malnutrition. At the end of the 2nd week, however,serum prealbumin in the exporimental group (24.31±4.80 mg / dl) retumed neariy to normal level, being significantly higher than that in the control group(15.10± 3.10 mg/ dl, P<0.01). At the end of the 4th week both serum albumin(3.90± 0.31 g/ dl) and prealbumin(27.33 ± 3.30 mg/ dl) in experimental group returned to normal, being also significantly higher than those in the control group(3.00± 0.23 g/ dl, P<005; 17.11 ± 322 mg/ dl, P<0.01).Anthropometry showed no sigmificant change between the two groups during ventila-tion. It is shown that nasal tube administration of“Nutritient”provides much higher energy and protein as compared with routine nasal feeding,and enables the patient to overcome protein deficiency and to reach positive nitrogen balance earlier.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1994年第8期527-530,共4页
Chinese Journal of Internal Medicine
关键词
肺心病
营养
人工呼吸
蛋白
Pulmonary heart disease Respiration artificial Nutrition
