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慢性酒依赖者认知功能的对照研究 被引量:20

The case-control study of cognitive function in chronic alcoholics
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摘要 目的评估慢性酒依赖者的认知功能状况。方法分别应用韦氏成人智力量表(WAIS)和韦氏记忆量表(WMS),对30例男性酒依赖者和30例匹配的正常对照者进行智能和记忆功能的评定,比较两组之间的差异,并对酒依赖者认知功能损害的危险因素进行相关分析。结果慢性酒依赖者的智商(FIQ)为86. 03±9. 87,记忆商(MQ)为61. 07±10. 13,均显著低于正常对照组(P<0. 05),智能和记忆量表的各因子分也表现出较为普遍的差异。相关分析表明,慢性酒依赖者的智商和记忆商数与饮酒时间呈显著负相关(r>0. 4,P<0. 01),与教育程度及习惯性饮酒开始年龄呈正相关(r>0. 2, P<0. 05 )。结论慢性酒依赖者存在显著的认知功能障碍。 ObjectiveTo evaluate the cognitive impairment of chronic alcoholics. MethodsThirty alcoholics and 30 matched healthy controls underwent intelligent and memory examination, with Wechsler adult intelligent scale (WAIS) and Wechsler memory scale (WMS), respectively. Results In chronic alcoholic subjects, the full intelligent quotient (FIQ) was 86.03±9.87,the memory quotient (MQ) was 61.07±10.13, compared with healthy control subjects, chronic alcoholics suffered significantly decreased intelligent quotient (IQ) and memory quotient (MQ), so did most factors of WAIS and WMS (P<0.05). The cognitive impairment of chronic alcoholics was negatively correlated with drinking duration, yet positively with educational levels and onset age of habitual drinking (r>0.3, P<0.05). ConclusionChronic alcoholics suffered cognitive impairment detected by WAIS and WMS.
作者 黄燕萍
出处 《中国行为医学科学》 CSCD 2005年第4期332-333,共2页 Chinese Journal of Behavioral Medical Science
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