摘要
目的 探讨染色体核型分析在少精子及无精子者中存在的意义。方法 对2 0 0 0年1月～2 0 0 4年8月来我院就诊的男性不育患者,凡精液记数小于2 0×10 6者取外周血淋巴细胞培养,常规制片G显带,进行染色体核型分析。结果 染色体核型正常6 5例,发现异常核型5 3例,异常检出率4 4 .92 %。异常核型主要涉及性染色体的数目异常,共计4 0例,占异常检出者的75 .4 7% ;性染色体结构异常12例,占异常检出者的2 2 .6 4 % ;常染色体1例,占异常检出者的1.89%。结论 对少精子及无精子者进行染色体核型分析十分必要,这不仅有助于病因诊断与分析,而且也有助于临床的处理和指导。
Objective: To study the meaning of the karyotype analysis in oligospermia and azoospermia. Methods: Blood samples from 118 patients whose sperm amount was less than 20×106 were regular cultured , proceeding ,G-banding and analysed. Results: 65 patients are normal; 53 patients are abnormal(44.92%). The abnormal is concerned sex chromosome's number that amounts to 40 patients.12 patients are the structure abnormal. One patient is autosome abnormal.Conclusion: It is necessary to take the Karyotype analysis of chromosome in patients who had oligospermia and azoospermia. It is not only to assist analysis the origin of the disease but also to supply important references for clinical therapy.
出处
《中国优生与遗传杂志》
2005年第5期49-50,共2页
Chinese Journal of Birth Health & Heredity
关键词
少精子症反无精子症
染色体异常
核型分析
Oligospermia and azoospermia
Chromosomal anomaly
Karyotype analysis
