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急诊肝移植治疗暴发性肝功能衰竭四例 被引量:3

Fulminant hepatic failure and emergency orthotopic liver transplantation: report of 4 cases
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摘要 目的总结暴发性肝功能衰竭实施紧急肝移植的经验。方法回顾性分析4例接受紧急肝移植的暴发性肝功能衰竭患者的临床资料。结果4例患者于术后12~48h神志恢复清醒,无手术并发症,术后有2例各发生急性排斥反应1次,经治疗逆转。4例患者均存活至今,肝功能良好,患者分别存活38、17、11及7个月,3例恢复工作。结论紧急肝移植是治疗暴发性肝功能衰竭的有效手段;围手术期的正确处理及手术时机的选择是提高紧急肝移植成功率的关键之一。 Objective To summarize the experience of emergency orthotopic liver transplantation (EOLT) in fulminant hepatic failure (FHF).Methods The clinical date of 4 cases of FHF successfully subject to EOLT were retrospectively analyzed.Results Four patients’ consciousness completely recovered in 12 to 48 h after operation, no surgical complication occurred; Acute rejection postoperatively occurred in 2 patients and reversed after treatment. Now 4 patients were survived for 38, 17, 11, 7 months respectively with good liver function, and 3 of them went to work again.Conclusion EOLT is an effective means to cure FHF. Choosing appropriate perioperative management and (operative) timing is essential to improve the successful rate of EOLT.
出处 《中华器官移植杂志》 CAS CSCD 北大核心 2005年第5期289-291,共3页 Chinese Journal of Organ Transplantation
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  • 1中华医学会传染病与,寄生虫病学分会,肝病学分会.病毒性肝炎防治方案[J].中华肝脏病杂志,2000,8(6):324-329. 被引量:14026
  • 2Lee WM. Acute liver failure. N Engl J Med, 1993, 329: 1862-1872.
  • 3Willams R, Wendon J. Indications for orthotopic liver transplantation on fulminant hepatic failure. Hepatology, 1994, 20:5-10.
  • 4Ascher NL, Lake JR, Emond JC, et al. Liver transplantation for fulminant hepatic failure. Arch Surg, 1993, 128:677-682.
  • 5Lo CM, Gertsch P, Fan ST. Living unrelated liver transplantation between spourses for fulminant hepatic failure-case report.Br J Surg, 1995, 82:1037.

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