期刊文献+

脑血管淀粉样变与高血压脑出血临床特征的研究 被引量:31

The study of clinical features of amyloid angiopathy hemorrhage and hypertensive intracerebral hemorrhage
原文传递
导出
摘要 目的比较颅内血管淀粉样变与高血压引起脑出血的临床、放射学和诊断的特点,对脑血管淀粉样变与高血压性脑出血的临床特征进行研究。方法对41例急性颅内血管淀粉样变脑出血病人的临床资料(包括年龄、血肿部位、形状、大小、是否伴发蛛网膜下腔出血和脑室出血等)、放射学诊断和病理学结果等因素进行分析,并与42例高血压性脑出血病人进行对照,行统计学分析。结果颅内血管淀粉样变出血组平均年龄明显高于高血压脑出血组,其出血主要位于脑叶的表面,呈分叶状或不规则状,易产生蛛网膜下腔出血和脑室出血,具有多发性和容易复发的特点。结论颅内血管淀粉样变出血在临床和影像学上具有一定的特征,但确诊需要病理学的诊断。 Objective The purpose of this study was to differentiate between cerebral amyloid angiopathy (CAA) and hypertension (HTN) based on hemorrhage pattern interpretation. Methods A retrospective analysis of 83 patients who were admitted to our service with an acute Intracerebral hemorrhage (ICH) . 41 patients with a histological proven diagnosis of cerebral amyloid angiography and 42 patients with a clear history of hypertension were investigated . Results Patients with a CAA-related ICH were significantly older than patients with a HTN-related ICH. Typical features of CAA-related ICH included lobar distribution affecting mainly the lobar superficial areas, lobulated appearance, rupture into the subarachnoid space, and secondary IVH from the lobar hemorrhage. Multiplicity of hemorrhage and repeated episodes also strongly suggest the diagnosis of CAA. Conclusions There are certain fertures in CAA on CT or MRI and in clinical. But the definite diagnosis of CAA -related hemorrhage requires a histopathological confirmation .
出处 《中华神经外科杂志》 CSCD 北大核心 2005年第4期236-239,共4页 Chinese Journal of Neurosurgery
  • 相关文献

参考文献19

  • 1Takahashi RH, Sawa H, Kuroda S, et al. Pathologic precesses leading to cerebral hemorrhage in amyloid angiopathy.Neuropathology, 1996,16:99-105.
  • 2Hendricks HT, Franke CL, Thunissen PH. Cerebral amyloid angiopathy: diagnosis by MRI and brain biopsy. Neurology, 1990,40:1308-1310.
  • 3Awasthi D, Voorhies RM, Eick J, et al. Cerebral amyloid angiopathy presenting as multiple intracranial lesions on magnetic resonance imaging. Case report. J Neurosurg, 1991,75:458-460.
  • 4Leblanc R, Preul M, Robitaille Y, et al. Surgical consideration in cerebral amyloid angiopathy. Neurosurgery, 1991,29:712-718.
  • 5许丹,杨春慧,王鲁宁.老年人脑淀粉样血管病的临床及病理研究[J].中华内科杂志,2003,42(8):541-544. 被引量:32
  • 6Lang E. W, Renya Zhan, Preul C , et al. Stroke pattern interpretation: the variability of hypertensive versus amyloid angiopathy hemorrhage. Cerebrovascular Disease. 2001, 12: 121-130.
  • 7Vonsattel JP, Myers rh, Hedley-Whyte ET, et al. Gerebral amyloid angiopathy without and with cerebral hemorrhages: a comparative histological study. Ann Neurol, 1991,30:637-649.
  • 8Itoh Y, Yamada M, Hayakawa M, et al. Cerebral amyloid angiopathy: a significant cause of cerebellar as well as lobar cerebral hemorrhage in the elderly. J Neurol Sci, 1993,116 : 135-141.
  • 9Guny E, Loiseau H, Rival J, et al. Amyloid angiopathy-related cerebellar hemorrhage. Surg Neurol, 1996,46:235-239.
  • 10Thomas T, Thomas G, McLendon G, et al. Beta-amyloid-mediated vasoactivity and vascular endothelial damage [ see comments ].Nature, 1996,380:168-171.

二级参考文献1

共引文献31

同被引文献269

引证文献31

二级引证文献261

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部