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丙型肝炎病毒的免疫逃逸机制 被引量:5

Mechanism of the immune escape of hepatitis C virus
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出处 《肝脏》 2005年第1期45-47,共3页 Chinese Hepatology
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  • 1Booth JC, Kumar U, Webster D, et al. Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients. Hepatology, 1998, 27: 223-227.
  • 2Tsai SL, Chen YM, Chen MH, et al. Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity.Gastroenterology, 1998, 115: 954-965.
  • 3Ruggieri A, Harada T, Matsuura Y, et al. Sensitization to Fas-mediated apoptosis by hepatitis C virus core protein. Virology, 1997,229:68-76.
  • 4Zhu N, Ware CF, Lai MM. Hepatitis C virus core protein enhances FADDmediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor. Virology, 2001,283: 178-187.
  • 5Watashi K, Hijikata M, Marusawa H, et al. Cytoplasmic localization is important for transcription factor muclear factor-kappa B activation by hepatitis C virus core protein through its amino terminal region. Virology,2001,286: 391-402.
  • 6Delhem N, Sabile A, Gajardo R, et al. Activation of the interferoninducible protein inase PKR by hepatocellular carcinoma derivel-hepatitis C virus corn protein. Oncogene, 2001,20:5836-5845.
  • 7Yao ZQ, Nguyen DT, Hiotellis AI, et al. Hepatitis C virus core protein inhibits human T lymphocyte response by a comploment-dependent regulatory pathway. J Immunol, 2001, 167:5264-5272.
  • 8Gale MJ, Kwieciszewski B, Dossett M, et al. Antiapoptotic and oncogenic potentials of hepatiis C virus are linked to interferon resistance by viral repression of the PKR prtein kinase. J virol, 1999,73:6506-6516.
  • 9Polyak SJ, Khabar KS, Rezeiq M, et al. Elevated levels of interleuk in-8in serum are associated with hepatitis C virus infection and resistance to interferon therapy. J Virol, 2001,75: 6209-6211.
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