摘要
目的观察安苏萌(人重组生长激素)在烧伤切、削痂及微粒皮移植后,微粒皮生长、创面愈合的疗效.方法选择烧伤总面积大于50%TBSA或Ⅲ°烧伤面积大于20%TBSA的患者62例,手术后第1天开始,每日12 U,皮下或肌内注射,连用10～15 d,以微粒皮生长快、创面愈合好、血浆白蛋白上升明显为有效.并回顾性分析,比较65例类似病例未用安苏萌治疗,设为对照组.结果治疗组微粒皮生长明显快于对照组,创面愈合显著加快,差异有显著意义(P＜0.05).创面愈合时间平均提前(14±1.6)d.结论安苏萌是大面积烧伤切、削痂及微粒皮移植术后,促进微粒皮生长,副作用少的有效重组人生长激素.
Objective To explore the effect of recombinant human growth hormone(rhHG) on particulate skin growth and wound healing in skin particulate transplate for cutting scab.Methods Sixty-two patients inflicted with burn of 50% TBSA or Ⅲ° burn of 20%TBSA were choser for A group(with 12IU/d of rhGH on 10～15d) in the study and observed the changes of particulate skin growth,wound healing,plasma levels of albumin.Take the results to compare with the control group(B group,non rhHG).Results The A group particulate skin growth significantly quicker than the B group,the wound healing faster than the control group and so on(P<0.05),and the times of wound healing significantly advanced by (14±1.6)d.Conclusion rhHG can significantly promote the particulate skin growth in transplate for great area cutting scab and have less side-effect.
出处
《中国基层医药》
CAS
2005年第3期323-324,共2页
Chinese Journal of Primary Medicine and Pharmacy
