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高密度脂蛋白胆固醇与冠心病的关系(附600例临床分析) 被引量:9

The Correlation between High-Density Lipoprotein Cholesterol and CHD(analysis of 600 cases)
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摘要 本文通过600例临床分析发现并确认:(1)冠心病心梗组的HDL-ch平均浓度为38.40~41.31mg%,非冠心病组的HDL-ch平均浓度为49.52~52.79mg%,前者明显低于后者;(2)HDL-ch值都在39mg%以下;(3)60岁以上的人群中TC水平与冠心病之间可能没有肯定的关系,而TC/HDL-ch比值升高较单纯TC的升高对诊断AS更有意义,该比值>4:1较比值<4:1时,冠心病的比例明显增加:(4)吸烟,肥胖者HDL-ch值较不吸烟,体重正常者明显降低,提示吸烟,肥胖也是通过降低HDL-ch促成AS病变的;(5)通过增加体育活动,减轻体重,停止吸烟,以及使用某些降脂药,均可提高血清HDL-ch水平,这有利于预防和控制AS的发生和发展。 Analysis of 600 cases reveal:(1)The mean concentration of HDL-ch in CHD MI group is 39.40~41.3 mg%.In non-CHD group,it is 49.52~52.79 mg%.The former is significantly lower than the latter.(2)When the concentration of HDL-ch is below 45 mg%,the lower is the value,the more serious is its influence on AS.The HDL-ch value in 71.0% of the CHD MI group is below 39 mg%.(3) There is no certain correlation between TC Ievel and CHD in over 60 years'group.The increase in TC/HDL-ch value is more significant than the increase in TC in the diagnosis of AS.When the TC/HDL-ch value is higher than 4:1, the incidence of CHD is significantly increased.(4) The HDL-ch of smoker and obesity is lower than that of non-smoker and nonobesity.This suggests that smoking and obesity may cause AS through lowering HDL-ch.(5) HDL-ch concentration can be elevated through exercise,lowering [body weight,stopping smoking or medication.
机构地区 北京安贞医院
出处 《心肺血管病杂志》 CAS 1994年第3期158-161,共4页 Journal of Cardiovascular and Pulmonary Diseases
关键词 高密度 脂蛋白胆固醇 冠心病 High-density lipoprotein cholesterol Coronary heart disease
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