摘要
目的: 探讨 50g糖筛查试验 (GCT) 筛查妊娠期糖尿病 (GDM) 的发病率、GCT血糖值与GDM、IGT检出率的关系, 孕妇年龄和体重因素对GDM发生的影响。方法: 采用回顾性研究的方法, 对 2003年 7月~2004年 6月广东省高要市人民医院产科门诊随机选择的 485例孕妇的临床资料进行分析。结果: ① 485例孕妇行GCT筛查, GDM、IGT的发病率分别为2 .3%、2. 7%。在GCT≥7 8mmol/L中, GDM的阳性率为 9. 8%, IGT的阳性率为 11 .6%, 需要行OGTT的人数为 23. 1%。在GCT≥8 3mmol/L中, GDM的阳性率为 13. 7%, IGT的阳性率为 16. 4%, 需要行OGTT的人数为 15. 1%。②空腹血糖对GDM和IGT的误诊分别为 72.7%和 84. 6%, 尿糖对GDM和IGT的误诊分别为 81. 8%和 92. 3%。③年龄 <25岁, GDM和IGT发病率0 9%, 年龄≥25岁, GDM和IGT发病率 6 1%, 两者比较P<0 05, 有显著性差异。孕前肥胖人群 (BMI≥25kg/m2 ) 的GDM和IGT的发病率高于非肥胖人群, 两者比较P<0 .01, 有极显著性差异。结论: ①妊娠期不能依靠空腹血糖和尿糖来筛查GDM。②年龄<25岁, BMI<25kg/m2, 无糖尿病高危因素, 可以不行GCT。③以GCT≥8 3mmol/L为切点, 可提高其诊断的特异性,减少OGTT检查的人数。
Objective:To study the relationship among incidence,glucose level of the GCT and GDM,the appropriate time of the 50g oral glucose challenge test (GCT) to screen gestational diabetes mellitus(GDM). To study the importance of the maternal age and weight of GDM methods.Methods:To analyse the feasibility of using the chinical date of 485 pregnant women and a retrospective study was made who underwent the GCT from July in 2003 to June in 2004 in the department of obsterice outpatient of Gaoyao City People's Hospital were collected, and a retrospective study was made.Results:(1)The determination was completed in 485 cases.(485 cases were completed,screen.) The incidence of GDM and IGT was 2.3% and 2.7%. Using GCT ≥ 7.8 mmol/L was the cutoff, the incidence of GDM and IGT was 9.8% and 11.6%. The requirement for OGTT was 23.1%. Using GCT ≥ 8.3 mmol/L was the cutoff, the incidence of GDM and IGT was 13.7% and 16.4%. The requirement for OGTT was 15.1%.(2) There would be 72.7%,84.6% of feastry blood glucose to misdiagnose of GCM and IGT. There would be 81.8% and 92.3% of urine glucose to misdiagnose of GDM and IGT.(3)The incidence of a disease was 0.9% when the women were younger than 25 years old, the incidence of GDM and IGT was 6.1% when the women were older than 25 years old, which was obviously higher than the other groups(P<0.05). The incidence gestation obesity. The incidence of GDM and IGT was higher than the before gestation obesity(BMI≥25kg/m^2),obviosuly lower than the other groups.Conclusion:(1)The determination of random blood glucose and urine glucose to screen GDN can' t replace the 50g GCT in the pregnant.(2) It is not necessary to screen GDM among the pregnant women younger than 25 years old, and BMI is< 25kg/m^2.(3) Using the cutoff 8.3 mmol/L of random blood glucose, the specificity would be increased and the requirement for OGTT would be lowered.
出处
《中国妇幼保健》
CAS
北大核心
2005年第6期704-706,共3页
Maternal and Child Health Care of China
关键词
妊娠期糖尿病
糖筛查试验
糖耐量试验
糖耐量减低
Gestational diabetes mellitus
Glucose challenge test
Glucose tolerance test
Impaired glucose tolerance
