摘要
采用人外周血淋巴细胞体外培养胞浆阻滞微核测试法，观察用３Ｈ－ＴｄＲβ线和６０Ｃｏγ线照射引起的剂量－效应关系，并计算了３Ｈ，ＴｄＲβ线的相对生物效应值。３Ｈ－ＴｄＲβ线内照射和６０ＣＯγ线外照射的剂量效应关系均符合Ｙ＝Ａ＋ＢＸ２＝ＣＸ２线性－平方数学模式，淋巴细胞微核频率随β线和γ线剂量的增加而增加。３Ｈ－ＴｄＲβ线的ＲＢＥ均值为１．１９，表明其β线产生的生物效应是γ线的１．１９倍。
Cytokinesis block micronucleus method was applied to study the
irradiation effects of β-rays fromincorporated 3H-TdR and 60Coγ
-rays on human peripheral blood lymphocytes in vitro. The
dose-res-ponse reiationships were fitted satisfactorily to the
linear-quadratic model: Y=A+BX+CX2. The fre-quency of microuclei
increased with increased doses of internAl β-irradiation and
external γ-irradia-tion. The average RBE of 3H一thymidine estimated
by comparing the two equations was 1. 19.
出处
《北京医科大学学报》
CSCD
1994年第4期251-253,共3页
Journal of Peking University(Health Sciences)
