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莫沙必利治疗反流性食管炎60例疗效观察 被引量:4

Clinical Study on the Curative Effect of Mosapride in Treating Reflux Esophagitis
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摘要 目的 观察莫沙必利治疗反流性食管炎的疗效及安全性。方法 治疗组 60例患者于 3餐前及睡前 2 0~ 3 0min口服莫沙必利 5~ 10mg ,4周为 1疗程 ,并与服用胃复安的对照组相比较。结果 莫沙必利可有效控制反流性食管炎的各种症状 ,使食管滴酸试验转阴、X线钡透胃食管反流消失 ,且无明显毒副作用。与胃复安疗效比较差异非常显著 (P <0 0 1)。结论 莫沙必利治疗反流性食管炎疗效显著且安全可靠 ,值得推广应用。 To observe the curative effect and safety of mosapride in treating reflux Esophagitis. 60 patients of the case group were treated with mosapride for 28 days, 3 times a day before meal and sleep with a dose of 5~10 mg orally, the result was compared with that of the control group treated with metoclopramide. Mosapride could effectively control various symptoms of reflux esophagitis with no obvious side effects. The difference was significant compared with the control group(P<0.01). [Conclusion] Mosapride is effective and reliable in treating reflux esophagitis.
出处 《职业与健康》 CAS 2005年第3期456-457,共2页 Occupation and Health
关键词 莫沙必利 反流性食管炎 疗效 Mosapride, Reflux esophagitis
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  • 1程书权,李家印.红霉素的非抗菌作用研究进展[J].临床荟萃,1994,9(22):1017-1019. 被引量:10
  • 2周智广.糖尿病性神经病变防治的新概念[J].中华内科杂志,1994,33(10):703-706. 被引量:30
  • 3[12]Bharucha AE, Camilleri M, Haydock S, et al. Effect of serotonin5-HT4 receptor antagonist SB-207266 on gastrointestinal motorand sensory function in human [J]. Gut, 2000, 47 (3): 667674.
  • 4[13]Chiba T, Tbomforde GM, Kost LJ, et al. Motilide accelerated regional gastrointestinal transit in dog [J]. Aliment PharmacolTher ,2000,14(7):955-960.
  • 5[14]Itoh Z. Motilin and cilinical application[J]. Peptide ,1997,18(4):593-608.
  • 6[15]Jailwala J, Imperiale TF,Kroenke K. Pharmacologic treatment ofthe irritable bowel syndrome: a systematic review of randomized,controlled trials[J]. Ann Intern Med ,2000,133(2): 136 - 147.
  • 7[16]Fioramonti J, Christen MO, Dupre I, et al. Effect of a selectivecalcium antagonist, pinaverium bromide, on sensitivity to rectaldistention in experimental inflammation in rats [J]. Gastroenterol, 1997, 112 (Suppl): A731.
  • 8[17]Moncada S, Palmer RMJ, Higgs EA. Nitric oxide: physiology,pathophysiology, and pharmacology [J]. Pharmacol Rev, 1991,43(1): 104 - 142.
  • 9[18]Orihata M, Sarna SK. Inhibition of nitric oxide synthase delaysgastric emptying of solid meals [J]. J Pharmacol Exp Ther,1994,271(2): 660-670.
  • 10[19]Scarpignato C, Pelosini I. Management of irritable bowel syndrome: novel approaches to the pharmacology of gut motility[J]. Can J Gastroenterol, 1999,13 (Suppl A):50A- 65A.

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