摘要
                
                    目的研究下颌逐步前伸过程中上气道形状的变化规律,了解藉改变颌位而改善通气的疗法的机制。方法对14例无鼾成年男性,使用特制口腔装置将下颌依次前伸,从初始咬合位0(F0),前伸50%(F50)、75%(F75),至前伸最大量100%(F100)。在此4个位置上行上气道磁共振扫描。测量和分析上气道各段轴截面矢向径/横向径的比值、矢向径和横向径相对于初始位置的改变百分率。结果随下颌逐步前伸,上气道轴截面矢向径/横向径的比值依次减小(P=00001),横向径变化率逐步增加(P=00023),而矢向径变化率的变化无统计学意义。结论在下颌逐步前伸过程中,上气道形状有更加横向扁圆的倾向,说明下颌前伸主要横向扩张上气道。
                
                Objective To examine adaptive changes in the shape of the upper airway during titrated mandibular advancement. Furthermore, to understand the mechanism of mandible-adjustable therapy to improve the ventilation. Methods Fourteen non-apnea participated in the study. A custom-made oral device was used to keep the mandible in titrated advancement at 0% (F_0), 50% (F_~50 ), 75% (F_~75 ), 100% (F_~100 ) of the maximum advancement. Magnetic resonance imaging was used to investigate the difference in the shape of upper-airway in these 4 positions. Changes in the anteroposterior direction(AP), lateral direction(Lat) and its ratio(AP/Lat) were calculated , which were transformed into the percentage of the original ones. Results The dose-dependent decrease of AP/Lat was found when the mandible was advanced(P=0.0001). Lateral change rate in percentage increased by degrees(P=0.0023), while the increase of anteropostierior change rate in percentage showed no statistical significance. Conclusion The shape of upper airway tended to be less round. The enlargement of upper airway during titrated mandibular advancement was mainly the result of enlargement in lateral direction.
    
    
    
    
                出处
                
                    《中华耳鼻咽喉头颈外科杂志》
                        
                                CAS
                                CSCD
                                北大核心
                        
                    
                        2005年第2期137-140,共4页
                    
                
                    Chinese Journal of Otorhinolaryngology Head and Neck Surgery
     
            
                基金
                    笹川医学奖学金资助项目(24期)
                    教育部留学回国人员科研启动基金资助项目(2003年)