摘要
目的探讨鼻眶脑型毛霉菌病的临床特征及诊断。方法回顾性分析2例鼻眶脑型毛霉菌病的临床资料并复习相关文献。结果2例患者,男女各1例,年龄为52岁、49岁,分别有糖尿病和地中海贫血史,病程中均有发热、颜面浮肿、视物模糊、鼻出血或涕中带血,鼻腔分泌物培养见毛霉菌生长。2例均在入院后1个月内死亡。结论鼻眶脑型毛霉菌病多继发于免疫力低下的严重疾病,早期诊断困难,病情进展迅速,死亡率高。鼻咽部X线、CT等影像学检查有助于本病的诊断,鼻腔分泌物真菌培养阳性确诊。
Objective To explore the clinical features and diagnosis of Rhino orbito cerebralmucormycosis.MethodsThe clinical data of 2 patients with Rhino orbito cerebral mucormycosiswere analyzed, and the related literatures were reviewed retrospectively.ResultsThe 2patients were a 52-year-old man and a 49-year-old woman, respectively. The male patientwas of diabete, and the female patient was of Mediterranean anemia. The clinical manifestationspresented fever, puffiness of face, blurred vision, and nasal hemorrhage in the duration ofillness. Mucor was found in the mycteric secretion. Both 2 patients died within one monthin hospital.ConclusionRhino orbito cerebral mucormycosis is always secondary from thesevere diseases with poor immunologic function. The diagnosis in the early stage is verydifficult. The patientss conditions get worse quickly, and the fatality rate is high. Theimaging examinations are helpful to diagnose, such as X-ray and CT scanning in nasopharynx.The comfirmed diagnosis relies on the positive results of the culture of mucor.[
出处
《罕少疾病杂志》
2005年第1期7-9,共3页
Journal of Rare and Uncommon Diseases
关键词
毛霉菌病
鼻眶脑型
诊断
mucormycosi
rhino orbito cerebral
diagnosis
