摘要
植物雌激素是一类天然的结构及生物活性均类似于雌激素的非甾体类化合物,可与雌激素受体结合,对内源性雌激素起双向调节作用。该文综述了近年来用植物雌激素对围绝经期综合征的动物实验、临床研究进展,发现与性激素替代疗法相比,植物雌激素提供了有效且更为安全的方法,但要成为性激素替代疗法的替代疗法则有待进一步的研究。
Phytoestrogen (PE) is a group of natural non steroid compound which displays estrogen like activity because of their structural similarity to human estrogens and exhibits high affinity binding to estrogen receptor beta. This article expounded relationship between pathogenesis of perimenopausal syndrome and shortage of estrogen, and reviewed progress in foreign animal expeimental and clinical researches on PE for prevention and treatment of perimenopausal syndrome in last six years. Compared with HRT, PE provided a more effective and safer method, but further research should be carried out for replacing HRT.
出处
《国外医学（妇幼保健分册）》
2004年第6期360-362,共3页
Foreign Medical Sciences (Section of Maternal and Child Health)
