摘要
综述了近年来清除试剂在液相组合化学中的应用,并介绍了一些采用清除试剂对液相化合物库进行分离和纯化的实例。对清除试剂进行了分类,各类清除试剂参与的液相反应以及被清除的非目标产物类型也作了相应的介绍。
Recent applications of scavenger reagent in solution phase combinatorial chemistry were reviewed in this paper.Examples of purification and resolution of solution compound library using scavenger reagent were introduced,and scavenger reagents used in solution phase combinatorial chemistry were classified.Properities of these reagents,impurities extracted by these reagents and category of scavenger reagent mediated reactions were also introduced.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2004年第6期728-732,共5页
Chemical Research and Application
基金
国家自然科学基金资助项目(20372021)
湖南省自然科学基金资助项目(03JJY3018)
关键词
清除试剂
液相组合化学
分离与纯化
液相化合物库
scavenger reagent
solution phase combinatorial chemistry
purification and resolution
solution phase compound library.
