不同麻醉方法对腹部肿瘤患者围手术期T淋巴细胞亚群和血流动力学的影响被引量：4

Effects of Different Anesthesia Methods on the T Lymphocyte Subsets and Hemodynamics of Patients with Abdominal Tumor in Peri operational Period

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摘要目的探讨不同麻醉方法对腹部肿瘤手术患者围手术期细胞免疫功能、平均动脉压和心率的影响。方法采用全麻(A组12例)、针刺复合全麻(B组10例)、硬膜外复合全麻(C组11例)、针刺加硬膜外复合全麻(D组11例)不同麻醉方法对腹部肿瘤手术患者进行麻醉,并观察各种麻醉前后不同时间患者的T淋巴细胞亚群及血流动力学变化。结果4组肿瘤手术患者的细胞免疫功能均下降,但C组和B组细胞免疫功能抑制的程度较轻,且在肿瘤切除一定时间后两组患者的细胞免疫功能有所改善;针刺复合全麻和针刺加硬膜外复合全麻对维持围术期血流动力学的平稳起一定作用。结论硬膜外复合全麻、针刺复合全麻是可供临床选择运用的良好麻醉方法,有利于腹部肿瘤患者免疫功能的及早恢复。 To explore the effects of different anesthesia Methods on the cellular immune function and mean arterial pressure, heart rate in patients with abdominal tumor in the peri operational period. MethodsPatients were anesthetized by general anesthesia (GA), combined acupuncture general anesthesia (AGA), combined epidural general anesthesia (EGA), and combined acupuncture epidural general anesthesia (AEA), respectively. Changes of T lymphocyte subsets and hemodynamics were observed at different time points before and after treatment. ResultsPatients' cellular immune function after GA was lowered, which could be alleviated by combination of GA with acupuncture anesthesia (AA) or with epidural anesthesia. Combined acupuncture drug anesthesia showed a stabilizing effect on hemodynamics in peri operational period to some extent. ConclusionEGA and AGA are good anesthesia choice in clinical practice, which would be favorable for early recovery of immune function in patients with abdominal tumor after operation.

作者顾陈怿楼怡蔡云彪胡军

机构地区上海中医药大学附属岳阳中西医结合医院麻醉科

出处《中国中西医结合杂志》 CAS CSCD 北大核心 2004年第11期973-975,共3页 Chinese Journal of Integrated Traditional and Western Medicine

关键词麻醉肿瘤围手术期 T淋巴细胞亚群血流动力学 different anesthesia methods peri operational period of abdominal tumor patients T lymphocyte subsets hemodynamics

分类号 R614 [医药卫生—麻醉学]

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1[1]Fernandez MC, Gottlieb M, Menitove JE. Blood transfusion and postoperative infection in orthopedic patients. Transfusion 1992;32(4) :318-322.
2[2]Groeben H, Schafer B, Pavlakovic G, et al. Lung function under high thoracic segmental epidural anesthesia with ropivacaine or bupivacaine in patients with severe obstructive pulmonary disease undergoing breast surgery. Anesthesiol 2002; 96 (3):536-541.
3[3]Fleisher LA, Anderson GF. Perioperative risk: how can we study the influence of provider characteristics? Anesthesiol 2002;96(5):1039-1041.
4[5]Han SH, Yoon SH, Cho YW, et al. Inhibitory effects of electroacupuncture on stress responses evoked by tooth-pulp stimulation in rats. Physiol Behav 1999;66(2) :217-222.
5[6]Gilliland HE, Armstrong MA, Una C, et al. The choice of anesthetic maintenance technique influences the anti-inflammatory cytokine response to abdominal surgery. Anesth Analg 1997 ;85(6):1394- 1398.