摘要
目的 调查我院 3年来医院感染革兰阴性分离菌及其药物敏感性 ,为临床合理应用抗生素提供参考。方法用纸片扩散法进行体外药敏试验 ,WHONET4软件进行统计分析。结果 3年间居前 3位的革兰阴性菌分别为铜绿假单胞菌、大肠埃希菌和肺炎克雷伯菌 ;对其常用抗生素的敏感性分析发现 ,3年间大多数抗生素的敏感性均有较大幅度下降 ,同时产 β-内酰胺酶 (ESBL s)菌逐年增多。结论 应注意合理使用抗生素并加强对细菌耐药性的全面监测。
OBJECTIVETo determine the antimicrobial susceptibility of G- isolates during the past 3 years to provide basis for reasonable use of antibiotics. METHODS K-B disc agar diffusion method was adopted to detect drug susceptibility in vitro and WHONET4 software was applied to analyze the data. RESULTSThe first three G- bacteria with highest number were Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumoniae respectively. The susceptibility of the most common-used antibiotics decreased greatly. In the meanwhile, ESBLs-producing strains were increasing year by year. CONCLUSIONSAntibiotics should be used reasonably and all-round supervision of drug resistance should also be strengthened.
出处
《中华医院感染学杂志》
CAS
CSCD
2004年第1期89-90,共2页
Chinese Journal of Nosocomiology
关键词
医院感染
革兰阴性菌
耐药性
Nosocomial infection
G- bacteria
Drug resistance
