摘要
结直肠手术前常规肠道准备包括机械准备和药物准备两种,其最初的目的是降低吻合口漏、腹腔和切口感染等并发症的发生率。目前国内很多医院尚沿用3天肠道准备法,而国际上肠道准备的方法已发生了很大的变化,西方国家在10余年前开始常规采用术前1天肠道准备,所用泻药主要是磷酸钠溶液和聚乙烯甘醇两种。目前认为过强的肠道机械和药物准备还可能造成肠道复合屏障的破坏,引起一系列并发症。国际上甚至有取消机械肠道准备的趋势,但尚无定论。国内需要一些设计良好的大规模临床研究来调整和规范结直肠手术前肠道准备的时间和强度。
The routine bowel preparation before colorectal surgery usually includes mechanical and medicine preparations? with the original purpose of reducing complications such as anastomosis leakage? wound? and abdominal infections. Many domestic hospitals are still employing the methods of three-day bowel preparation? while in the West? the way of this preparation has dramatically changed. In last decade? one-day preparation has been widely accepted internationally? with two major medications of sodium phosphate and polyethylene glycol frequently used in the clinic. It has also been indicated that excessive mechanical and medicinal bowel preparations exert harmful effects on the combined intestinal barrier? and may result in various complications. A few reports have suggested to omit the mechanical bowel preparation before surgery? which is still under controversy? however? well-designed clinical trials are needed to readjust and regulate the duration and intensity of bowel preparation before colorectal surgery in China.
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2004年第5期591-594,共4页
Acta Academiae Medicinae Sinicae
关键词
肠道准备
肠道屏障
磷酸钠
聚乙烯甘醇
bowel preparation
intestinal barrier
sodium phosphate
polyethylene glycol
