摘要
本研究采用分子生物学、免疫组织化学、病理和电镜等实验方法,探讨祛瘀生肌法外用药物(复黄膏)创面修复的作用机理,并进一步观察其临床疗效。实验结果表明祛瘀生肌法促进局部创面组织IGFImRNA、FN增加,并呈良好的量效关系(P<0.01);组织形态学表现优于阳性对照药(白玉膏)。临床疗效同对照药比较,有显著性差异(P<0.05)。结论:祛瘀生肌法能够提高创面修复的质量和速率。
Thisstudyhadusedmolecularbiology,immunohistochemistry,pathologicalandelectromicroscopictechniquestostudymechanismofwoundhealingoftheexternaldrug(YellowRestoringOintment)usedinthestagnationremovingandmuscleproducingmethodandtofurtherobserveitsclinicaleffect.TheexperimentalresultsshowedthatthestagnationremovingandmuscleproducingmethodcouldpromotelocalwoundtissueIGFImRNA,increaseFNandwasinabetterdoseeffectrelationship(P<0.01)andthattheexpressioninhistomorphologywasbetterthaninthepositivecontrolherbalmedicine(WhiteJadeOintment).Therewassignificantdifferenceinthetherapeuticeffectincomparisonwiththecontrolmedicine(P<0.05).Theconclusionisthatthestagnationremovingandmuscleproducingmethodcanenhancethequalityandvelocityofwoundhealing.
出处
《上海中医药大学学报》
CAS
1999年第2期34-37,共4页
Academic Journal of Shanghai University of Traditional Chinese Medicine
基金
国家自然科学基金
国家中医药管理局科研基金
关键词
祛瘀生肌法
复黄膏
白玉膏
创面愈合
Thestagnationremovingandmuscleproducingmethod,YellowRestoringOintment,WhiteJadeOintment,woundhealing