摘要
目的 观察介入栓塞治疗对Graves'病临床疗效。方法 采用美国通用公司的GEPrestageSI数字减影X线机 ,经皮从股动脉穿刺引入导管选择性插至两侧甲状腺上动脉 ,用聚乙烯醇(PVA)栓塞后 ,再用明胶海绵填塞。结果 8例均在术后2周左右甲状腺明显缩小 ,1～2月后血清T3、T4、FT4接近正常 ,自觉症状在2周后开始缓解 ,1～2月后恢复正常。彩色多普勒检查证实甲状腺缩小外 ,还显示血管变细、血流量明显减少、血流速度缓慢。血钙、血磷正常 ,未见眼征变化 ,随访1年无发生甲状腺功能减退。结论 介入栓塞治疗Graves'病疗效好、安全、简便、痛苦较手术切除小 ,并发症少 ,不失为临床治疗Graves'病或作术前准备另一有效的新方法 ,最适宜于抗甲状腺药物过敏。
Obejective To estimate the effect of thyroid arterial embolization in patients with Graves'disease. Methods Selective arteriˉography of superior thyroid arteries,followed by embolization using polyviny1alcohol(PVA)and collagen sponge sequentially,was performed by percuˉtaneous transluminal digital subtraction angiography(GE Prestage SI). Results Of all eight cases,the size of tyhyroid glands had decreased significantly and symptoms became remission in two weeks.They became euthyroid in one to two months.We confirmed that the size of thyroid glands and the average diameters and the flowof the superior arteries decreased,measured using Doppler US respectively During the one year following-up period,serum calcium and phosphorus kept normal level,no hypothyroid and aggravation of ophthalmopathy occurred. Conclusion Interventional embolization is a novel,effective,convenient and less suffering therapy to treat Graves'disease and prepare for operation,especially to those who are allergic to oral antithyroid drugs and unable to tolerate operation and radioactive iodine.
出处
《浙江临床医学》
2004年第10期837-838,共2页
Zhejiang Clinical Medical Journal
