摘要
分析肾炎后慢性肾功能衰竭 (CRF)不同虚证患者尿蛋白 (Upro)、血清免疫球蛋白A(IgA)、甲状旁腺素 (PTH)、纤维连接蛋白 (FN)等指标的变化情况。采用比色法、透射比浊法及酶法等技术分别检测CRF虚证患者生化指标。结果 :脾肾阳虚型患者尿蛋白含量、2 4小时尿蛋白定量明显升高 (P <0 0 5或P <0 0 1) ;免疫、激素指标结果显示 ,脾肾阳虚型的总花环、免疫球蛋白IgA、IgG明显下降 ,甲状旁腺素显著升高 ,与其余虚证比较有显著差异 (P <0 0 5 ) ;血浆载脂蛋白结果显示 ,脾肾阳虚型载脂蛋白B明显升高 (P <0 0 5 )。提示慢性肾衰不同虚证患者中尤以脾肾阳虚型的生化指标变化最为显著 。
The changes of Upro, IgA, PTH and FN in patients with nephritic chronic renal failure (CRF) of different deficiency syndromes were observed. Results: In cases of spleen-kidney yang deficiency, Upro and 24h-Upro rose obviously (P<0.01-0.05), total wreath, IgA and IgG obviously decreased and PTH increased remarkably, in comparison with other deficiency syndromes, P<0.05; apolipoprotein B increased (P<0.05). It is indicated that, in patients with CRF, above indexes changed significantly in the cases of spleen-kidney yang deficiency, which provides diagnostic evidences for spleen-kidney yang deficiency.
出处
《上海中医药杂志》
北大核心
2004年第10期3-5,共3页
Shanghai Journal of Traditional Chinese Medicine
基金
上海市科委资助项目 (98ZB14 0 32 )