摘要
目的 观察和评价老年性黄斑变性 (ARMD)的荧光素眼底血管造影 (FFA)图像特征及其临床应用价值。方法 对 110例ARMD患者的 15 2眼行FFA检查 ,并对检查结果进行综合分析。结果 FFA图像显示 15 2眼中 ,干性型 117眼 (76 .97% ) ,湿性型 35眼 (2 3.0 3% ) ;湿性型中有典型黄斑下脉络膜新生血管 (CNV)2 1眼 (6 0 .0 0 % ) ,隐匿型CNV 6眼 (17.14 % ) ,黄斑结瘢 8眼 (2 2 .86 % ) ;在明确CNV定位和分型中 ,典型CNV呈颗粒状 9眼、斑片状 7眼、车轮状 5眼 ,隐匿型CNV呈血管性色素上皮脱离 4眼、血管性色素上皮病变 2眼。视力 <0 .3的干性型 2 6眼 (占干性型总数 2 2 .2 2 % ) ,湿性型 33眼 (占湿性型总数 94 .2 9% ) ;视力 >0 .3的干性型 91眼 (占干性型总数 77.78% ) ,湿性型 2眼 (占湿性型总数 5 .71% )。结论 FFA可早期发现黄斑下典型CNV ,并能确定其位置、范围、数目及性质 ,从而指导临床治疗。隐匿型CNV结合吲哚青绿血管造影 (ICGA)可发现FFA未能显示的典型CNV。
Objective To observe the characteristics of fundic fluorescein angiography (FFA) and to evaluate its clinical value in diagnosis of age-related macular degeneration(ARMD). Methods Analyzed the results of FFA examination on 152 eyes in 110 cases of ARMD.Methods FFA showed among 152 eyes of 110 cases; 117 eyes were of dry type senile macular degeneration accounting for 76.97 %, 35 eyes were of wet type which accounted for 23.03 %, 21 eyes (60.00 %) had apparant subretinal-choroidal neovascularization (CNV) beneath the macula. There were 6 eyes having subretinal-choroidal occult CNV which accounted for 17.14% and 8 eyes of macular scar which accounted for 22.86 %. In the location and pattern of CNV, the classic CNV showed granular shape in 9 eyes, patchy in 7 and wheel shape in 5 eyes. The occult CNV included 4 eyes with vascular pigmented epithelial detachment, 2 eyes with vascular pigmented epithelial lesion.Results Visual accuity analysis indicated that 26 eyes of dry type had visual accuracy <0.3 (22.22% in all dry type eyes), while 33 eyes of wet type had visual accuity<0.3 (94.29 % in all wet eyes). 91 eyes of dry type had visual accurity >0.3 (77.78% in all dry type eyes), whereas only 2 eyes of wet type had visual accuracy>0.3, which accounted for 5.71% in all wet-type eyes.Conclusion FFA can be used to diagnose the classical CNV in early stage and to clarify the location, range,number and characteristics of CNV, thus provide guidance to clinical therapy. Combined with indocyanine green angiography (ICGA), the occult CNV can further be diagnosed not solely by FFA. CNV is the main cause of poor visual accuracy and blindness in ARMD.
出处
《上海医学》
CAS
CSCD
北大核心
2004年第8期600-602,F003,共4页
Shanghai Medical Journal
