摘要
目的 :探讨荨麻疹患者的细胞免疫功能。方法 :对 60例荨麻疹患者用流式细胞仪检测外周血T淋巴细胞及其亚群并与 40例健康志愿者作对照。结果 :荨麻疹患者CD3 + 及CD4+ 细胞明显降低 ,与健康对照组比较差异有显著意义 (P <0 0 1) ,其中以急性荨麻疹患者改变最为明显。结论 :荨麻疹患者存在着T淋巴细胞免疫功能紊乱现象 ,在荨麻疹的发病中 ,不但有体液免疫参与 ,而且细胞免疫在荨麻疹的发病中亦有一定的作用。
Objective To study the function of cellular immunity of patients with urticaria. Methods T-lymphocytes subpopulations of the peripheral blood in 60 patients with rticaria and 40 healthy controls were examined by flow cytometry. Results The number of CD3 + and CD4 + cells in the urticaria group were significantly lower than those in the control group (P<0.01), especially in patients with acute urticaria. Conclusion There was immunologic dysfunction of T lymphocyte in the patients with urticaria, and not only humoral immunity but also cellular immunity plays a certain role in the pathogenesis of urticaria.
出处
《实用医学杂志》
CAS
2004年第5期510-511,共2页
The Journal of Practical Medicine
基金
杨森科学研究基金资助课题 (JS2 0 0 1 0 0 8)
