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Protective effect of Apocynum venetum (罗布麻) against lipid peroxidation damage of erythrocyte membrane

Protective effect of Apocynum venetum (罗布麻) against lipid peroxidation damage of erythrocyte membrane
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摘要 Objective: To investigate the protective effect of Apocynum venetum on lipid peroxidation damage of erythrocyte membrane. Methods: Model of lipid peroxidation of erythrocyte membrane was manufactured by three kinds of radicals generation systems. To set up a normal control group (NC),a model control group (MC),and four Apocynum venetum groups(A.V). Observation was made on the content of malondialdehyde (MDA). Results: Compared with MC group,all of the four Apocynum venetum groups dose-dependently inhibited the increases of MDA content in the membrane induced by xanthine - xanthine oxidase system,H 2O 2 or UV light. Conclusions: Apocynum venetum may protect erythrocyte membrane from the lipid peroxidative damage induced by radicals. Objective: To investigate the protective effect of Apocynum venetum on lipid peroxidation damage of erythrocyte membrane. Methods: Model of lipid peroxidation of erythrocyte membrane was manufactured by three kinds of radicals generation systems. To set up a normal control group (NC),a model control group (MC),and four Apocynum venetum groups(A.V). Observation was made on the content of malondialdehyde (MDA). Results: Compared with MC group,all of the four Apocynum venetum groups dose-dependently inhibited the increases of MDA content in the membrane induced by xanthine - xanthine oxidase system,H 2O 2 or UV light. Conclusions: Apocynum venetum may protect erythrocyte membrane from the lipid peroxidative damage induced by radicals.
出处 《中药药理与临床》 CAS CSCD 2004年第3期16-18,共3页 Pharmacology and Clinics of Chinese Materia Medica
关键词 罗布麻 自由基 红细胞膜脂质过氧化损伤 细胞保护 中医药疗法 药理试验 Apocynum venetum radicals erythrocyte membrane lipid peroxidation
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  • 4徐光,上海医科大学学报,1993年,3卷,187页

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