摘要
目的 :探讨糖尿病孕妇胎盘微绒毛的定量变化过程 ,进而解释其形态学的改变特征及围生儿患病率高的原因。方法 :取足月糖尿病孕妇及正常孕妇胎盘各 12例 ,制成超薄切片 ,光镜下及电镜下观察 ,对合体细胞微绒毛进行体视学的测量。结果 :糖尿病孕妇的胎盘合体细胞微绒毛体积密度 (VV) ,表面积密度 (SV) ,数密度 (NV)小于对照组 ,差异均有显著性意义 (P <0 .0 5 )。结论 :糖尿病孕妇胎盘功能及代偿能力降低 ,其改变与缺氧时胎盘变化相一致 ,反映糖尿病孕妇可能存在缺氧。糖尿病孕妇应适当增加供氧 ,对其进行严密监护 。
Objective: To explores the change of placenta chorion in pregnant women with diabetes mellitus, and further to explain the morphologic features and the association with prenatal morbidity rate. Methods: Placenta tissues were obtained from 12 healthy pregnant women and 12 pregnant women with diabetes mellitus to observe the cells of chorion and to investigate on its morphology by light microscopy and electro-microscopy. Results: The Vv, Sv, and Nv in syncytial cells of placenta chorion from diabetes mellitus women were significantly lower than those in healthy women. There was significantly difference (P<0.05). Conclusions: The placenta function and compensation ability in pregnant women with diabetes mellitus decrease. Their morphologic change is similar to that of anoxic placenta that means anoxia may exists in pregnant women with diabetes mellitus. It is very important to increase offering oxygen and to monitor rigorously to these diabetes mellitus pregnant women for preventing from fetal death of anoxia.
出处
《实用妇产科杂志》
CAS
CSCD
北大核心
2004年第4期217-218,i009,共3页
Journal of Practical Obstetrics and Gynecology
基金
黑龙江省自然科学基金资助项目 (D992 6)
关键词
糖尿病
胎盘
绒毛膜
显微电子
Diabetes mellitus
Placenta
Chorion
Fiber electron
