摘要
目的观察冠心病心绞痛伴心理障碍患者在正规抗心绞痛治疗基础上联合应用抗焦虑抑郁药物后的再次发病和再次住院情况。方法选择我院门诊或住院具有典型心绞痛的冠心病患者,进行躯体化症状量表及Zung焦虑、抑郁自评量表评分,共120例冠心病心绞痛伴心理障碍患者,随机分为对照组(单纯抗心绞痛治疗)60例和干预组(抗心绞痛治疗基础上加用抗焦虑抑郁药物)60例,进行12个月的随访,观察两组患者再次发病和再次住院次数。结果经Ridit分析,干预组再次发病次数、再次住院次数较对照组均明显减少(P<0.05)。结论冠心病心绞痛伴心理障碍患者加用抗焦虑抑郁药物治疗后能有效减少再次发病和再次住院次数。
Objective To observe the angina relapse and hospital readmission after conventional anti-angina treatment combined with anti-depressant drugs in patients with angina accompanied with psychological disorder.Methods 120 outpatients and inpatients with angina were graded by Somatic Self-rating Scale before they were randomly divided into control group(anti-angina treatment alone,60 cases) and intervention group(anti-angina treatment combined with anti-depressant drugs,60 cases).All the patients were followed up for 12 months.The angina relapse and hospital readmission were both observed.Results After Ridit analysis,the relapse and hospital readmission times in intervention group were significantly reduced compared with those of the control group(P < 0.05).Conclusion The combination of anti-depressant drugs can significantly reduce the times of relapse and hospital readmission for patients with angina accompanied with psychological disorder.
出处
《中国全科医学》
CAS
CSCD
北大核心
2013年第27期3176-3178,共3页
Chinese General Practice
基金
浦东新区卫生局卫生科技项目(PW2010A-40)
关键词
冠心病
心绞痛
心理障碍
抗焦虑药
抗抑郁药
Coronary artery disease
Angina
Mood disorders
Anti-anxiety agents
Antidepressive agents
