摘要
目的：评价Ｃ－Ｌ短柱瓣植入人体后的血液动力学性能。方法：慢性风湿性心脏病患者１２８例随机分成３组，分别采用Ｃ－Ｌ短柱瓣、ＳｔＪｕｄｅ双叶瓣、Ｍｅｄｔｒｏｎｉｃ－Ｈａｌ单叶瓣作心脏瓣膜替换术，比较３种瓣膜植入人体后７２ｈ内血液动力学的变化。结果：应用Ｃ－Ｌ短柱瓣组，其术后的血液动力学变化趋势与应用ＳｔＪｕｄｅ组或Ｍｅｄｔｒｏｎｉｃ－Ｈａｌ组相仿，在术后２４ｈ后均能显著改善患者的血液动力学（Ｐ＜０．０５），３组间无统计学差异（Ｐ＞０．０５）；而且术后早期３组血管活性药物的使用亦无明显差异（Ｐ＞０．０５）。结论：Ｃ－Ｌ短柱瓣植入人体内，对血液动力学的影响与目前已公认优良的人造心脏瓣膜相比无明显差异。
Objectives: To evaluate the hemodynamic performance of C L pugestrut heart valvular prosthesis in patients undergoing heart valve replacement. Methods: One hundred and twenty eight patients with rheumatic heart disease (RHD) were divided randomly into three groups: C L group with the implantation of C L pugestrut valve, St Jude group with St Jude bileaflet valve and Medtronic group with Medtronic Hall valve. Results: Mean pulmonary arterial pressure, pulmonary arterial wedge pressure, systemic vascular resistance index and pulmonary vascular resistance index were significantly reduced immediately after heart valve replacement in three groups while cardiac index, stroke index, left cardiac work index, left ventricular stroke work index, right cardiac work index and right ventricular stroke work index were significantly improved (P<0.05) in all three groups after 24 h postoperatively. There were no statistical differences among the three groups in regarding to the above hemodynamic parameters as well as the postoperative usage of administered vasoactive agents(P>0.05).Conclusion: C L pugestrut valve implanted in vivo results in an excellent hemodynamics in patients undergoing cardiac valve replacement.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1997年第S1期10-14,共5页
Academic Journal of Second Military Medical University
关键词
风湿性心脏病
瓣膜替换术
血液动力学
人造心脏瓣膜
rheumatic heart disease
heart valve replacement
hemodynamics
heart valve prostheses
