摘要
目的 探讨糖尿病肾病患者凝血和纤溶方面的特点。方法 选取血浆D-二聚体作为研究指标,分别测定糖尿病肾病、尿毒症组和慢性肾小球肾炎、尿毒症组血浆D-二聚体含量进行对照研究,D-二聚体用单抗 ELISA双抗体夹心法进行定量测定。结果 糖尿病肾病组血浆D-二聚体含量显著高于慢性肾小球肾炎组,且二者D-二聚体含量皆高于正常值。结论 糖尿病肾病患者存在明显的高凝与继发性纤溶亢进。
Objective To investigate the character of blood - clotting and fibrinolysis in diabetic nephropathy patients. Methods Determine plasma D-dimer in two groups of uremic patients diabetic nephropathy and chronic nephritis. D-dimer was determined quantitatively by enzyme linked immunosorbent assay. ELISA of double antibody-sandwiched method. Results D-dimer of the diabetic nephropathy group was significantly higher than the chronic nephritis group. D-dimer of both groups was higher than the normal range. Conclusion There is significantly hypercoagulation and secondary hyperfibrinolysis in diabetic nephropathy patients.
出处
《青岛医药卫生》
1999年第6期413-413,共1页
Qingdao Medical Journal
