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地塞米松对普鲁卡因全麻术后镇痛效应的影响

Influence of Dexamethasone on Analgesic Effect of Novocaine in General Anesthesia
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摘要 目的 采用普鲁卡因配伍地塞米松静脉滴注,观察研究地塞米松对全麻术后镇痛效应的影响。方法 70例臂丛神经修复、背阔肌皮瓣修复和胸脐皮瓣修复手术的病人,随机分为两组,A组采用1%普鲁卡因、0.1%氯胺酮和0.1%司可林混合液静脉滴注和复合氨氟醚气管内吸入,B组在A组静脉用药的基础上静注地塞米松0.15mg·kg^(-1)。两组均选用气管内插管静吸互补全麻,比较术后镇痛时间的作用效果。结果 术后镇痛时间B组显著长于A组(P<0.01)。结论 地塞米松有增强普鲁卡因全麻术后镇痛效应的作用。 Objective To observe the influence of dexamethasone on postoperatively analgesic effect on general anesthesia by venoclysis of novocaine combined with dexamethasone. Methods 70 cases who underwent nerve repair of brachial plexus,transplantation of umbilico-costal flap or dorsal latissimus flap were randomly divided into two groups. In group A, novocaine combined with retamine hydrochloride and suxamethonium chloride was administered by venoclysis and enflurance was inhaled at the same time. In events of group B,dexamethasone was also administered by intravenous injective besides administration of group A. All the cases were intubated intratracheally and supplied with intravenous anesthesia. The postoperatively analgesic time and effect were compared. Results The postoperatively analgesic time of group B was remarkably longer than that of group A (P<0. 01). Conclusion Dexamethasone can improve the postoperativeiy analgesic effect of novocaine in general anesthesia.
出处 《青岛医药卫生》 2001年第6期405-406,共2页 Qingdao Medical Journal
关键词 地塞米松 普鲁卡因 全身麻醉 Dexamethasone Procaine General anesthesia.
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