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多氯联苯CB-28对牙鲆肝脏中EROD活性的诱导作用研究 被引量:10

Induction of EROD activity in Paralichthys olivaceus by polychlorinated biphenyl CB-28
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摘要 将牙鲆作为受试生物,暴露于不同浓度梯度的多氯联苯CB-28中72h后,发现受试生物肝脏内的EROD活性随着加标量的增加显著上升,并与污染物浓度之间存在着显著的正相关关系,因此牙鲆肝脏内的EROD活性与环境中特定污染物浓度之间存在着定量响应关系,EROD的这个特性可以作为评估海洋生态环境健康的预警指标.同时也讨论了EROD活性测定的最佳实验条件,并剖析了EROD活性作为监测指标应用的局限性. The test organisms Paralichthys olivaceus were exposed to CB-28 with different spiked concentrations. After 72 h, EROD activities in livers of test organisms were measured. It was found that EROD activities significantly mounted up with the increase of spiked quantity. Therefore, there existed a quantitative responsive relationship between EROD activities and specific pollutant concentrations. In the meantime, the optimal conditions for analysis of EROD activity were discussed. The limitation of EROD activities as a monitoring parameter was also analyzed.
出处 《海洋学报》 CAS CSCD 北大核心 2003年第S2期35-40,共6页
基金 国家"九五"攻关资助项目(96-922-01-02).
关键词 多氯联苯 EROD 牙鲆 生物效应 细胞色素P450 PCBs EROD flounder bioeffect cytochrome P450
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参考文献7

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