摘要
目的通过观察患者用药前后肺功能的变化,探讨噻托溴铵治疗稳定期慢性阻塞性肺疾病(COPD)的疗效。方法将60例稳定期COPD患者随机分成实验组和对照组,实验组30例吸入噻托溴铵粉雾剂18μg,每天上午1次;对照组30例口服茶碱缓释片,0.1 g/次,2次/d,治疗疗程4周,测定患者用药前后肺功能的变化。结果两组治疗后肺功能指标均有所改善,实验组较对照组各项指标改善明显(P<0.05)。结论稳定期COPD患者规律吸入噻托溴铵可明显改善肺功能和临床症状。
Objective To evaluate the effect of tiotropium using in Stable Chronic Obstructive Pulmonary Diaease(COPD) through observing the changing of patients' lung function before and after using tiotropium.Methods Dividing 60 patients with stable COPD into 2 groups(experimental group and control group) randomly,30 patients as the experimental group inhaled tiotropium 18 μg once every morning;30 patients as the control group took orally Theo-Dur 0.1g each time,twice a day for 4 weeks.Then testing the changing of patients' lung function before and after given the medicines above.Results Lung function of two groups were both improved,and the improvement of experimental group was obviously better than the control group(P < 0.05).Conclusion Patients with stable COPD regularly inhale tiotropium can obviously improve their lung function and clinical symptoms.
出处
《黑龙江医学》
2013年第8期693-694,共2页
Heilongjiang Medical Journal
关键词
噻托溴铵
慢性阻塞性肺疾病
肺功能分析
Tiotropium
Chronic Obstructive Pulmonary Diaease(COPD)
Pulmonary function analysis