摘要
目的分析脑膜瘤病理类型、发生部位与瘤周水肿的关系。方法回顾性分析428例脑膜瘤病人的临床资料,病理类型参照WHO 2007年版中枢神经系统肿瘤分型,同时分析术前MRI瘤周水肿特点。结果出现瘤周水肿211例(49.30%)。WHO分级高的脑膜瘤比分级低者水肿程度高(P<0.001),且在WHOⅠ级的脑膜瘤中,四种常见的脑膜瘤水肿程度较其他脑膜瘤低(P=0.006)。不同部位的脑膜瘤瘤周水肿程度没有统计学差异(P=0.113),但大脑凸面肿瘤较颅底肿瘤瘤周水肿发生率高(P<0.05)。结论脑膜瘤瘤周水肿与脑膜瘤发生部位及病理类型有关。分析肿瘤周围水肿情况,对肿瘤病理类型的初步判断和肿瘤切除方式的选择有重要意义。
Objective To explore the relations of pathological type and site to peritumoral edema in meningeomas.Methods The clinical data of 428 patients with meningeoma were analyzed retrospectively.The pathological types of meningeomas were identified according to WHO 2007 edition of central nervous system tumor classification,and peritumoral edema on preoperative MRI was analyzed.Results Peritumoral edema was seen in 211 cases(49.30%).The peritumoral edema in WHO high grade of meningeomas was more serious than that in low grade(P<0.001).And in WHO grade I meningeomas,the degree of peritumoral edema was less in 4 common types of pathology than other types(P=0.006).There was no significant difference in degree of peritumoral edema between sites of meningeoma(P=0.113),while the tumor site was associated with incidence of peritumoral edema which was higher in convexity meningiomas than in skull base meningiomas(P<0.05).Conclusions The peritumoral edema is related to the site and pathological type of meningeoma.Understanding peritumoral edema is of great significance for the preliminary judgment of pathological type and choice of surgical treatment in meningeomas.
出处
《中国微侵袭神经外科杂志》
CAS
北大核心
2011年第4期168-170,共3页
Chinese Journal of Minimally Invasive Neurosurgery
关键词
脑膜瘤
瘤周水肿
病理类型
meningeoma
pathology
peritumoral edema
