Expression of insulin-like growth factor Ⅱ and its receptor in hepatocellular carcinogenesis 被引量：24

Expression of insulin-like growth factor Ⅱ and its receptor in hepatocellular carcinogenesis

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摘要 INTRODUCTIONInsulin-like growth factor Ⅱ(IGF-Ⅱ) is a mitogenic peptide of 74 kD and is mostly synthesized in fetal liver tissue .IGF-Ⅱ is believed to play an important role in fetal growth and development and is involved in cellular proliferation and differentiation[1-5]. Recently ,several researchers have reported increased expression of the IGF-Ⅱgene in human hepatocellular carcinoma (HCC) and adjacent non-cancerous liver tissues [6-10].

作者 Zi Rong Fan Dong Hua Yang Jun Cui Han Rong Qin Chun Chi Huang Department of Gastroenterology, Zhujiang Hospital. The First Military Medical University, Guangzhou 510282.Guangdong Province. China

出处《World Journal of Gastroenterology》 SCIE CAS CSCD 2001年第2期285-288,共4页 世界胃肠病学杂志（英文版）

基金 Project supported by the National Nature Science Foundation of China,No.39470774

关键词 liver neoplasms/pathology insulin-like growth factor Ⅱ/biosynthesis receptors somatomedin/biosynthesis RNA messenger/biosynthesis in situ hybridization hepatitis chronic/pathology liver neoplasms/pathology insulin-like growth factor H/biosynthesis receptors,somatomedin/biosynthesis RNA, messenger/biosynthesis in situ hybridization hepatitis,chronic/pathology

分类号 R735.7 [医药卫生—肿瘤]

作者简介 Zi Rong Fan, graduated from The First Military Medical University,physician-in-chief, lecturer, master degree of gastroenterology, he has published 20 papers.Zi Rong Fan. Department of Gastroenterology,Zhujiang Hospital. The First Military Medical University, Guangzhou 510282,Guangdong Province. ChinaTel. 0086-20-85143361

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参考文献4

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7Xiao-Yan Cao Jie Liu Zhao-Rui Lian Marcy Clayton Jia-Lu Hu Ming-Hua Zh Dai-Ming Fan Mark Feitelson Institute of Digestive Diseases,Xijing Hospital,Fourth Military Medical University,Xi’an 710033,Shaanxi Province,ChinaDepartment of Pathology & Cell Biology,Thomas Jefferson University,Philadelphia,PA19107 USADepartment of Pathology,Second Military Medical University,Shanghai 200433,China.Cloning of differentially expressed genes in human hepatocellular carcinoma and nontumor liver[J].World Journal of Gastroenterology,2001,7(4):579-582. 被引量：7
8Zheng-Xu Wang~1 Gui-Fang Hu~1 Hong-Yang Wang~2 Meng-Chao Wu~2 1 Department of General Surgery,Chinese PEA General Hospital of Lanzhou Military Command,Lanzhou 730050,Gansu Province,China2 Eastern Hepatobilliary Surgical Hospital,Second Military Medical University,Shanghai 200438,China.Expression of liver cancer associated gene HCCA3[J].World Journal of Gastroenterology,2001,7(6):821-825. 被引量：9
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10Gao-Quan Gong Xiao-Lin Wang Jian-Hua Wang Zhi-Ping Yan Jie-Min Cheng Sheng Qian Yi Chen Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China.Percutaneous transsplenic embolization of esophageal and gastrio-fundal varices in 18 patients[J].World Journal of Gastroenterology,2001,7(6):880-883. 被引量：14

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10Lian Jun Yang,Yan Fang Sui,Zhi Nan Chen Department of Pathology, Fourth Military Medical University. Xi’an 710032, Shaanxi Province, China.Preparation and activity of conjugate of monoclonal antibody HAb18 against hepatoma F( ab′ )_2 fragment and staphylococcal enterotoxin A[J].World Journal of Gastroenterology,2001,7(2):216-221. 被引量：20

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