摘要
目的:探讨冠心病稳定期血瘀证及其兼证与冠状动脉造影Gensini评分的关系。方法:选取131例经冠状动脉造影证实的冠心病患者,记录其稳定期中医证候与血瘀证计分,并根据患者冠状动脉造影特点进行Gensini评分,分析其血瘀证及其兼证、血瘀证计分与其冠状动脉病变特点和Gensini评分之间的关系。结果:冠心病稳定期患者以血瘀证、痰浊证、气虚证最为多见,分别占64.9%(85/131)、63.4%(83/131)、64.9%(85/131)。血瘀证患者冠状动脉病变长度与Gensini评分的数值均高于非血瘀证者(P<0.05,P<0.01)。在血瘀证兼证中,血瘀兼痰浊患者的冠状动脉病变长度与Gensini评分的数值均高于非血瘀证者(P<0.05);血瘀证计分>9分的患者,其冠状动脉病变长度长于血瘀证计分≤9分的患者(P<0.05);冠心病稳定期患者血瘀证计分与Gensini评分无明显相关性(Pearson相关系数为0.104,P=0.241)。结论:血瘀证是冠心病稳定期患者的常见证候,血瘀证计分反映了患者血瘀证严重程度,稳定期患者的血瘀证计分与冠心病患者发病时冠状动脉病变严重程度没有相关性。
Objective:To study the correlation of blood stasis syndrome or its accompanied syndromes with Gensini score in patients with coronary heart disease (CHD) in stable condition.Methods:The syndrome types of traditional Chinese medicine (TCM) and blood stasis score in 131 CHD patients confirmed by coronary angiography were recorded. Gensini score was calculated according to the coronary pathological characteristics showed by angiography. The correlations of blood stasis syndrome and its accompanied syndromes with coronary lesion and Gensini score were analyzed.Results:Among the TCM syndrome types,blood stasis,turbid phlegm and qi deficiency were the most common syndromes,revealed in 85 patients (64.9%),83 patients (63.4%) and 85 patients (64.9%),respectively. The coronary lesion length and Gensini score in the patients with blood stasis syndrome were much higher than those in the patients with non-blood stasis syndrome (P<0.05 or P<0.01). In the subtypes of blood stasis,the coronary lesion length and Gensini score in the patients with blood stasis accompanied by turbid phlegm syndrome were higher than those in the patients with non-blood stasis syndrome (P<0.05). And in the patients whose blood stasis syndrome score was more than 9 points,the coronary lesion length was higher than that in the patients whose blood stasis syndrome score was less than 9 points (P<0.05). Besides,with bivariate analysis,the blood stasis syndrome score showed no correlation with Gensini score (Pearson correlation coefficient was 0.104,P=0.241).Conclusion:Blood stasis syndrome is the most common TCM syndrome in CHD patients in stable condition. The blood stasis syndrome score is proportional to coronary lesion length,and reflects the severity of coronary lesion.
出处
《中西医结合学报》
CAS
2010年第9期848-852,共5页
Journal of Chinese Integrative Medicine
基金
"十一五"国家科技支撑计划资助项目(No.2006BAI04A01)
首都医学科技发展基金(中医药类)资助项目(No.2005-SF-I-014)
关键词
冠心病
血瘀
GENSINI评分
coronary heart disease
blood stasis
Gensini score
