摘要
目的研究体重在女性儿童青少年青春发育过程中的作用及可能的机制。方法采用横断面调查和纵向随访结合的方式,对288名5～16岁健康女性儿童青少年进行连续4年的随访,观察第2性征发育、身高、体重、体脂比例,测定血瘦素和胰岛素样生长因子-1(IGF-1)水平,分析青春发育始动和月经初潮的影响因素。结果女性儿童青少年血瘦素水平从13岁开始显著增加,至16岁达峰值;IGF-1与青春发育始动年龄相关;体重指数和体脂比例对青春发育始动无显著影响,但与月经初潮年龄呈负相关。结论体重可能参与了青少年女性月经初潮的发生。
Objective To investigate the possible effects and roles of bodyweight on the puberty onset in adolescent girls.Methods Totally 288 Chinese female children and adolescent girls aged 5 to 16 were followed up yearly for four consecutive years.The height,bodyweight,fat percentage,sexual characteristics,and the serum levels of leptin and insulin-like growth factor-1(IGF-1 ) were studied to analyze the influential factors of puberty onset and age of monarche.Results The serum level of leptin elevated signifanctly...
出处
《中国医学科学院学报》
CAS
CSCD
北大核心
2010年第1期25-28,共4页
Acta Academiae Medicinae Sinicae
