摘要
目的 探讨大鼠短期服用硝酸稀土对胃粘膜抗氧化能力的影响。方法 按分组给药 30d后检测胃粘膜超氧化物歧化酶 (SOD)和过氧化脂质 (LPO)含量。结果 硝酸稀土 2 .0mg/kg和混合稀土 0 .1mg/kg组SOD含量显著升高 ;硝酸稀土 2 0 .0mg/kg组LPO含量显著升高 ,混合稀土 2 .0mg/kg和 0 .1mg/kg组LPO显著降低。结论 短期口服 2 0 .0mg/kg硝酸稀土可促进胃粘膜内脂质过氧化过程 ,0 .1、2 .0mg/kg的硝酸稀土可增强胃粘膜抗氧化能力 。
Objective To research the effect of rare earth nitrate on the antiozx idation ability of gastric mucosa in rats.Methods After 30 day group administration,the level of SOD and LPO in gastric mucosa was determined.Results In 2.0 mg/kg rare earth nitrate group and 0.1 mg/kg mixed rare earth group,SOD significantly increased while in 2.0 mg/kg rare earth nitrate group,LPO greatly increased and in 2.0 mg/kg,0.1 mg/kg mixed rare earth group LPO greatly decreased.Conclusion Oral taking 20.0 mg/kg rare ...
基金
国家自然科学基金资助项目 [2 9890 2 82 3( 2 ) ]
