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TNF-α与INF-γ在肠结核患者血清中的表达研究

The study of the level of TNF-α and INF-γ in serum of patients with intestinal tuberculosis
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摘要 目的研究肠结核患者血清INF-γ和TNF-α的表达变化。方法采集肠结核患者不同治疗阶段及健康志愿者的血清,采用ELISA检测其INF-γ表达水平,RIA检测TNF-α表达水平。结果肠结核患者血清INF-γ和TNF-α的表达均显著高于健康对照组,并且随着患者病情变化而变化。结论测定INF-γ和TNF-α的表达可以反映和预测肠结核患者的病情变化。 Objective To study the level of TNF-α and INF-γ in serum of patients with intestinal tuberculosis.Methods Collected serum of patients and volunteer.ELISA was used to detect the level of INF-γ,and RIA was used to detect the level of TNF-α.Results The level of TNF-α and INF-γ in patients serum of intestinal tuberculosis were higher than that of control group,and the change of the level associated with the change of pathogenetic condition.Conclusion Detecting the level of TNF-α and INF-γ in patients serum of intestinal tuberculosis may predict the change of pathogenetic condition.
出处 《基层医学论坛》 2009年第17期483-485,共3页 The Medical Forum
关键词 肠结核 TNF-Α INF-Γ Intestinal tuberculosis TNF-α INF-γ
作者简介 郭振文,男,40岁,本科学历,毕业于广州医学院,主治医师.E--mail:suchunkang@126.com
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