摘要
目的 :观察静脉滴注 (静滴 )地尔硫对不稳定型心绞痛合并顽固性高血压病人的治疗效果和安全性。方法 :31例不稳定型心绞痛合并顽固性高血压且扩血管药物疗效不好的病人 ,静滴地尔硫2 0～ 5 0mg后 4 8h内 ,观察心绞痛症状、血压、心率变化、心电图转变及副作用。结果 :静脉滴注地尔硫治疗心绞痛总有效率为 97%。 31例中有 30例用药 4 8h内心绞痛次数减少 (3.2± 2 .1)次 ,发作持续时间缩短 (11± 4 )min ,静脉滴注地尔硫后血压、心率明显降低 ,收缩压由 (2 2± 3)kPa降为 (18±4 )kPa (P <0 .0 5 ) ;舒张压由 (12 .8± 1.8)kPa降为(10 .3± 2 .3)kPa (P <0 .0 5 )。 11例病人用药后ST段恢复正常或明显改善。副作用少。结论 :静脉滴注地尔硫对不稳定型心绞痛合并顽固性高血压的治疗有效、安全。
AIM: To study the efficacy and safety of diltiazem intravenous dripping in the treatment of unstable angina patients (UAP) accompanied obstinate hypertension. METHODS: Thirty one UAP with obstinate hypertension, who could not be controlled enough by other vessel expansionary medicines,were treated with diltiazem iv,gtt 20 50 mg. The symptom of ischemic,the change of blood pressure,heart rate and EKG as well as adverse reactions were observed for 48 h. RESULTS: (1)The number of ischemic in thirty patients...
出处
《中国新药与临床杂志》
CAS
CSCD
北大核心
2001年第S1期31-33,共3页
Chinese Journal of New Drugs and Clinical Remedies
