摘要
目的:观察植物蛋白对肝炎后肝硬化患者的营养支持作用。方法:选择有低蛋白血症的肝炎后肝硬化患者85例,其中植物蛋白饮食组（实验组）50例,对照组35例,分别给予以植物蛋白为主的高热量食谱和医院常规食谱,4周后观察其临床症状、血清白蛋白、血清总胆红素和血清丙氨酸氨基转移酶的变化,评价其效果。结果:与治疗前相比,实验组和对照组各项症状在治疗后均有显著改善（P<0.05）。两组之间比较,实验组患者疲劳感和纳差的改善情况优于对照组（P<0.05）;其它症状改善程度两者相似。两组治疗后肝功能各项指标均明显改善（P<0.01）;血清白蛋白治疗前后差值在两组间比较有显著差异（P<0.01）;血清丙氨酸氨基转移酶治疗前后差值在两组间比较亦有显著差异（P<0.05）;血清总胆红素治疗前后差值在两组间无显著差异（P>0.05）。结论:高能量植物蛋白饮食有利于改善肝炎后肝硬化患者的营养状态。
Objective: Out purpose was to observe the supportive effect of plant protein in patients with hepatic cirrhosis secondary to hepatitis. Methods: Eighty-five patients with hepatic cirrhosis secondary to hepatitis and hypoproteine-mia were included. The treatment group (50 cases) and the control group (35 cases) received high caloric diet that mainly composed of plant protein and routine diet in hospital respectively. At the end of 4 weeks, we observed and assessed changes in clinical symptoms, serum albumin, serum total bilirubin and alanine aminotransferase. Results: Clinical symptoms significantly improved in both groups after treament ( P < 0. 05 ). The improvement of fatigue and anorexia in treatment group was more obvious than that in the control group ( P < 0.05). The extents of improvement of other symptoms in two groups were similar. Indexes of hepatic function significantly improved after treatment ( P <0.01) . The difference of serum albumin between before and after treatment was significat between the two groups ( P <0.01). The difference of alanine aminotransferase between before and after treatment was also significant between groups ( P < 0. 05 ). No significant change in serum total bilirubin before and after treatment was observed between groups ( P > 0. 05). Conclusion: High-caloric plant protein dietary was of benefit to patients with hepatic cirrhosis secondary to hepatitis.
出处
《中国医科大学学报》
CAS
CSCD
北大核心
2002年第z1期30-31,34,共3页
Journal of China Medical University
关键词
肝硬化
植物蛋白
饮食
hepatic cirrhosis
plant protein
dietary
作者简介
张韬，研究生
