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比较蛋白质组研究方法学进展 被引量：2

The Progress in Methodology of Comparative Proteomics
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摘要 比较蛋白质组学针对不同空间、不同时间上动态变化着的蛋白质组的整体进行比较,分析不同蛋白质组之间在表达数量、表达水平和修饰状态上的差异,可以发现与病变相关的特异蛋白质,对疾病的诊断和治疗具有重要意义。本文对比较蛋白质组研究在方法学方面的最新进展加以系统综述,引用文献33篇。 Comparative proteomics is to differentiate the expression patterns of the dynamic proteomes changed with space and time.Through comparing the expression and modification of different proteomes,the disease related proteins could be found,which have greatsignificance to disease diagnose and treatment.The lasted development of the methodological research on comparative proteomics wasreviewed in this paper,and 33 papers were cited.
作者 郑彦 邵淑娟
机构地区 大连大学附属新华医院 大连医科大学
出处 《生命科学仪器》 2006年第6期19-22,共4页 Life Science Instruments
关键词 比较蛋白质组 双向凝胶电泳 质谱 液相色谱 Proteomics MS,HPLC,2D-GEL
分类号 TH79 [机械工程—精密仪器及机械]
作者简介 邵淑娟,博士,教授,大连医科大学,地址:大连市中山路458号,大连医科大学,电话:0411-84721576,email: shaoshujuan@sohu.com 联系人
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参考文献28

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二级参考文献17

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共引文献8

同被引文献17

  • 1高秦,刘宏伟,金岩,聂鑫,刘源.人牙周膜干细胞的体外分离、纯化及初步鉴定[J].实用口腔医学杂志,2006,22(1):34-37. 被引量：34
  • 2白晓卉,于修平.比较蛋白质组学研究进展[J].医学综述,2006,12(17):1071-1073. 被引量：3
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生命科学仪器
2006年 第6期

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