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帕罗西汀与氟西汀治疗冠心病并发抑郁症的临床观察 被引量:6

A Comparative Study of Paroxetine and Fluoxetine in the Treatment of Depression in Patients with Coronary Arerty Disease
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摘要 目的观察帕罗西汀与氟西汀治疗冠心病伴抑郁的疗效及安全性。方法82例冠心病后抑郁患者,随机分为两组,分别采用帕罗西汀与氟西汀治疗8周,采用汉密顿抑郁量表(HAMD),及副反应量表(TESS)评定疗效及不良反应。结果帕罗西汀与氟西汀疗效相近,但帕罗西汀起效快,不良反应少。结论帕罗西汀与氟西汀治疗冠心病后抑郁一样安全有效。 Objective To comparative the efficacy and adverse effect of paroxetine and fluoxetine in the treatment of depression in patients with coronary arerty disease. Methods The patients who met the CCMD-3 were randomly divide into two groups. One group was treated with paroxetine, and the other with fluoxetine for 8 weeks. The efficacy and adverse effect were evaluated by HAMD, HAMA and TESS. Results Paroxetine was as effective as fluoxetine in the treatment of depression in patients with coronary arerty disease. Conclution Paroxetine is efficacions for depression in patients with coronary arerty disease, with superior safey profile over.
作者 秦玉花 陈雷
机构地区 中国
出处 《中国健康心理学杂志》 2007年第3期256-257,共2页 China Journal of Health Psychology
关键词 帕罗西汀 氟西汀 冠心病 抑郁症 Paroxetine Fluoxetine Depression Coronary arerty disease
作者简介 秦玉花,E-mail:qyhzhq@163.com
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参考文献3

  • 1[1]Schleifer SJ,Macari-Hinson MM,Coly DA,et al.The nature and course of depression following myocardial infarction.Arch Inter Med,1989,149:1785-9
  • 2[2]Barefoot JC,Helms MJ,Mark DB,et al.Depression and longterm mortality risk in patients with coronary artery disease Am J Cardiol,1996,78:613-7
  • 3[3]Sullivan MD,La Croix AZ,Spertus JA,et al.Five-year prospective study of the effects of anxiety and depression in patients with coronary artery disease.Am J Heart,2000,86:1135-8

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