摘要
骨关节炎(OA)是一种常见的关节退行性疾病,以疼痛、畸形、关节活动障碍等为特点,给患者个人、家庭和社会造成了沉重的负担。外用药物是一大类常用的治疗OA的干预措施,然而当前临床实践中存在各种不同类型、不同成分、不同作用机制、不同剂型的外用药物。目前在临床实施过程中缺少外用药物应用的共识。因此,如何有效、正确地选择外用药物是临床医生关注的问题。该指南由中华医学会骨科学分会关节外科学组发起,采用推荐意见分级的评估、制订及评价(GRADE)分级体系,科学性、透明性和适用性的评级工具(STAR)和指南研究与评价工具Ⅱ(AGREEⅡ)及国际实践指南报告规范(RIGHT)等方法,遴选出医生最为关注的9个临床问题,并最终形成9条循证医学推荐意见。本指南旨在提高医疗机构治疗OA过程中,外用药药物使用的科学性并最终提升以患者为中心的医疗服务质量。
Osteoarthritis(OA)is a highly prevalent degenerative joint disease,characterized by pain,deformity and limited function,which represents a substantial burden for affected individuals,families,and the society.Topical medicine is a large class of commonly used interventions for the treatment of OA.However,in current clinical practice,there are various types of topical medicine with different components,mechanisms of action and varied dosage forms.At present,there is no consensus on the application of topical medicine in clinical implementation.Therefore,how to choose topical medicine effectively and correctly is an issue that clinicians concern about.The present guideline was initiated by the Joint Surgery Branch of the Chinese Orthopaedic Association.The Grading of Recommendations Assessment,Development and Evaluation(GRADE)approach,the scientificity,transparency and applicability ranking tools(STAR),the Appraisal of Guidelines for Research and Evaluation(AGREE)Ⅱ,and the Reporting Items for Practice Guidelines in Healthcare(RIGHT)were utilized to formulate nine evidence-based recommendations based on nine most concerned clinical questions from practitioners in primary clinics in China.This guideline intended to improve the scientificity of topical medicine for OA ultimately.
作者
中华医学会骨科学分会关节外科学组
徐永清
王坤正
李川
钱东阳
王斌
王健
邢丹
杨佩
Joint Surgery Group of Orthopaedic Branch of Chinese Medical Association;Xu Yongqing;Wang Kunzheng(不详;the 920th Hospital of Joint Service Force of PLA)
出处
《中华关节外科杂志（电子版）》
CAS
CSCD
2023年第3期301-307,共7页
Chinese Journal of Joint Surgery(Electronic Edition)
基金
国家自然科学基金面上项目(82072392)
云南省骨科与运动康复临床医学研究中心(202102AA310068)
云南省科技人才与平台计划项目(202105AD160027)
关键词
骨关节炎
诊疗准则
外用药
Osteoarthritis
Clinical practice guideline
Administration
topical
作者简介
通信作者:徐永清,Email:xuyongqingkm@163.net;通信作者:王坤正,Email:wkzh1955@163.com
