摘要
Background:The purpose of this analysis is to evaluate the current evidence with regard to the effectiveness and safety between coiling and clipping in patients with ruptured intracranial aneurysms(RIAs).Methods:We performed a meta-analysis that compared clipping with coiling between July 2000 and September 2021.PubMed,EMBASE,and the Cochrane Library were searched for related articles systematically.And the treatment efficacy and postoperative complications were analyzed.Results:We identified three randomized controlled trials and thirty-seven observational studies involving 60,875 patients with ruptured cerebral aneurysms.The summary results showed that coiling was related a better quality of life(mRS0-2;OR=1.327;CI=1.093-1.612;p<0.05),a higher risk of mortality(OR=1.116;CI=1.054-1.180;p<0.05),higher rate of rebleeding(RR=1.410;CI=1.092-1.822;p<0.05),lower incidence of vasospasm(OR=0.787;CI=0.649-0.954;p<0.05),higher risk of hydrocephalous(RR=1.143;CI=1.043-1.252;p<0.05),lower risk of cerebral infarction(RR=0.669;CI=0.596-0.751;p<0.05),lower risk of neuro deficits(RR=0.720;CI=0.582-0.892;p<0.05),and a lower rate of complete occlusion(OR=0.495;CI=0.280-0.876;p<0.05).Conclusion:Coiling was significantly associated with a better life quality(mRS0-2),a lower incidence of postoperative complications,and a higher rate of mortality,rebleeding,hydrocephalous,and a lower rate of complete occlusion than clipping.
作者简介
Correspondence:Xin-yu Yang,yangxinyu@tmu.edu.cn
